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The COST Manual of Laboratory Animal Care and Use: Refinement, Reduction, and Research book cover

1st Edition

The COST Manual of Laboratory Animal Care and Use Refinement, Reduction, and Research

Edited By Bryan Howard, Timo Nevalainen, Gemma Perretta Copyright 2011
439 Pages 43 B/W Illustrations
by CRC Press

Judge Your Practices Against This Benchmark Manual COST Action B-24 established four working groups to research and discuss issues relevant to laboratory animal science. These included the housing of animals, environmental needs, refinement of procedures, genetically modified animals, and cost-benefit analysis. Based on the groups’ findings, The COST Manual of Laboratory Animal Care and Use:... Read more

Introduction; Bryan Howard, United Kingdom
Design and Oversight of Laboratory Animal Facilities; Dag Sørensen, Norway; Heinz Brandstetter, Germany;Nikolaos Kostomitsopoulos, Greece; and Richard Fosse, France
Housing and Care of Laboratory Animals; Hanna-Marja Voipio, Finland; Ping-Ping Tsai, Germany; Heinz Brandstetter,Germany; Marcel Gyger, Switzerland; Hansjoachim Hackbarth, Germany;Axel Kornerup Hansen, Denmark; and Thomas Krohn, Denmark
Animal Needs and Environmental Refinement; Vera Baumans, The Netherlands; Hanna Augustsson, Sweden;and Gemma Perretta, Italy
Ethical Evaluation of Scientific Procedures: Recommendations for Ethics Committees; Rony Kalman, Israel; I Anna S Olsson, Portugal; Claudio Bernardi, Italy; Frank van den Broek, The Netherlands; Aurora Brønstad, Norway;Istvan Gyertyan, Hungary; Aavo Lang, Estonia; Katerina Marinou,Greece; and Walter Zeller, Switzerland
Reduction by Careful Design and Statistical Analysis; Michael Festing, United Kingdom
Animal Models: Selecting and Preparing Animals for a Study; Patrick Hardy, France and Sarah Wolfensohn, United Kingdom
Creation of Genetically Modified Animals; Belen Pintado, Spain and Marian van Roon, The Netherlands
Management of Genetically Modified Rodents; Jan-Bas Prins, The Netherlands
Impact of Handling, Radiotelemetry, and Food Restriction; Timo Nevalainen, Finland: Marlies Leenaars, The Netherlands;Vladiana Crljen, Croatia; Lars Friis Mikkelsen, Denmark; Ismene Dontas,Greece; Bart Savenije, The Netherlands; Carlijn Hooijmans, The Netherlands;and Merel Ritskes-Hoitinga, The Netherlands
Basic Procedures: Dosing, Sampling and Immunisation; Ismene Dontas, Greece; Jann Hau, Denmark; Katerina Marinou, Greece;and Timo Nevalainen, Finland
Imaging Techniques; Aurora Brønstad, Norway and Ismene Dontas, Greece
Anaesthesia and Analgesia; Patricia Hedenqvist, Sweden and Paul Flecknell, United Kingdom
Use of Humane Endpoints to Minimise Suffering; Coenraad Hendriksen, The Netherlands; David Morton, United Kingdom;and Klaus Cussler, Germany
Euthanasia; Luis Antunes, Portugal
Education, Training and Competence; Bryan Howard, United Kingdom; Katey Howard, Spain; and Peter Sandøe, Denmark
Animal Experimentation and Open Communication; Ann-Christine Eklöf, Sweden; Anne-Grethe Berg, Norway;and Jon Richmond, United Kingdom

Biography

Bryan Robert Howard is the former Director of Animal Welfare at the University of Sheffield.

Timo Nevalainen is a Professor of the National Laboratory Animal Center at the University of Kuopio.

Gemma Perretta is the Head of the Division of Special Zoology and Animal Models for the Institute of Neurobiology and Molecular Medicine of the Italian National Research Council in Rome.

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