284 Pages
44 B/W Illustrations
by
CRC Press
284 Pages
44 B/W Illustrations
by
CRC Press
284 Pages
44 B/W Illustrations
by
CRC Press
Also available as eBook on:
This book is a comprehensive review of thrombin, especially as regulatory protease. The ready availability of highly purified thrombin has stimulated rapid advances in the cell biology of this important macromolecule. The text focuses on research findings from the discovery of thrombin by Andrew Buchanan in 1842 to the present. A substantial amount of this work was conducted by the author and his... Read more
Preface
Acknowledgements
About the Author
1. The History of Thrombin
2. The Formation of Thrombin
3. Structural Biology of Thrombin
4. The Use of Protein Engineering (Mutagenesis) to Study Functional Regions in Thrombin Expression and Characterization of Recombinant Thrombins
5. Chemical Modification of Thrombin
6. The Interaction of Thrombin with Fibrinogen and Fibrin
7. Thrombin and Platelets
8. Inhibitors of Thrombin
Index
Biography
Roger L. Lundblad is an independent consultant based in Chapel Hill, North Carolina. He is also an adjunct professor of pathology at the University of North Carolina, Chapel Hill.
