The only guide to focus primarily on current molecular methods of diagnosis and early stage evaluation, this reference presents the latest techniques and technologies for dementia identification and evaluation, including neuropathological strategies, neuropsychological tests, biomarkers, CT, MRI, functional MRI, PET, and SPECT. Offering practical care and examination guidelines, each chapter provides findings that are particularly relevant for the assessment of disorders such as Alzheimer's disease, dementia with Lewy bodies, vascular dementia, and fronto-temporal dementia.
Table of Contents
The Clinical Issues. Neuropsychological Screening and Advanced Neuropsychological Tests.
Biomarkers in Blood and Cerebrospinal Fluid. Genetics: Facts and Perspectives. Approaches to the Identification of Novel Diagnostic and Therapeutic Targets in Dementia. Quantitative and Functional MRI Techniques. Perfusion SPECT. FDG PET: Imaging Cerebral Glucose Metabolism with Positron Emission Tomography. Imaging of Neurotransmitter Systems in Dementia. Development and Application of beta-Amyloid Imaging Agents in Alzheimer's Disease. A View on Early Diagnosis of Dementias from Neuropathology. Guideline and Perspective. Index
Karl Herholz, Daniela Perani, Chris Morris