1st Edition

The Endometrial Factor A Reproductive Precision Medicine Approach

Edited By Carlos Simón, Linda C. Giudice Copyright 2017
288 Pages 300 Color & 100 B/W Illustrations
by CRC Press

284 Pages 300 Color & 100 B/W Illustrations
by CRC Press

At the dawn of precision medicine, there is a new opportunity for novel approaches to understand, diagnose and treat endometrial disorders that affect fertility, reproductive outcomes, and women’s health more broadly. Herein, the editors have assembled critically evaluated state-of-the-art chapters presenting basic and clinical knowledge about the human endometrium that impacts or will impact... Read more

Preface. Foreword: An eye to the future. Highlights on the dynamism and multifunctionality of human endometrium in the era of precision medicine. Diagnosis of the Endometrial Factor: New imaging diagnostics. Molecular diagnosis of endometrial receptivity. Molecular diagnosis of endometriosis. Microbiological diagnosis: The human endometrial microbiome-endometritis. Hysteroscopy: An invasive diagnosis. Personalization of the Endometrial Factor: The endometrium in Polycystic Ovary Syndrome. Obesity and the endometrium. Uterine fibroids and the endometrium. New knowledge about adenomyosis. Therapeutic Options of the Endometrial Factor: Hormonal regulation of the endometrium and the effects of hormonal therapies. Abnormal Uterine Bleeding (previously Dysfunctional Uterine Bleeding): How to manage. Inflammation of the endometrium in reproduction. Empirical treatments to improve receptivity: Why not?. Endometrial scratching. Stem Cell Therapies for Atrophic Endometrium and Asherman´s Syndrome. Gestational surrogacy. Uterine transplantation. The Ultimate Goal: Embryo/fetal-maternal cross-talk. Embryo transfer: Fresh, deferred, personalized? Reproductive and obstetrical outcomes.

Biography

Carlos Simón M.D., PhD is Professor of Obstetrics and Gynecology at the University of Valencia, Spain; Adjunct Clinical Professor, Department of Ob/Gyn, Stanford University School of Medicine, CA, USA; Scientific Director of Instituto Valenciano de Infertilidad (IVI) and IGENOMIX. Linda C Giudice MD, PhD, MSc is Distinguished Professor and Chair, The Robert B. Jaffe, MD Endowed Professor in the Reproductive Sciences, University of California at San Francisco, CA, USA.