1st Edition
The Human Genome in Health and Disease A Story of Four Letters
Chapter 1. Introduction
Chapter 2. A molecular disorder
Chapter 3. A code of life
Chapter 4. The genome
Chapter 5. Variants in the human genome sequence and their biological significance
Chapter 6. The critical protein coding sequences
Chapter 7. Triplet repeats and neurodegenerative disorders
Chapter 8. The untranslated parts of a message
Chapter 9. Exons, introns and a royal bleeding disorder
Chapter 10. The regulation of transcription
Chapter 11. The non-coding RNAs
Chapter 12. Computational methods are critical in the analysis of molecular sequences
Chapter 13. Diagnosing the genome
Chapter 14. Correcting genome errors
Chapter 15. Epilogue
Biography
Tore Samuelsson
"... an excellent primer on the molecular and biochemical underpinnings of disease. The author walks us through how the genome is structured and regulated, interspaced with detailed explanations of how changes in the genome result in biological function and human disease. He includes personal touches that help humanize the material..." - The Quarterly Review of Biology, 95(2).
"Although the material is appropriate for advanced biology students, this volume would also be suitable for those with limited knowledge of biology due to the detailed and careful walkthrough of the topic matter that makes it approachable for nonspecialists, especially for fledgling computational biologists or clinical geneticists, and even for nonacademics who wish to better understand their own genome." - William Gillis, Biological Sciences, State University of New York College at Old Westbury
