1st Edition

The Immunogenetics of Autoimmune Diseases, Volume II



ISBN 9780849368981
Published November 30, 1990 by CRC Press
336 Pages

USD $550.00

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Book Description

Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex MHC; elucidation of its gene structure and polymorphism, as well as the molecular basis of MHC restriction; the arrangement, expression, and regulation of immunoglobulins; definition of the structure of the T cell receptor and organization of its genes; and the characterization of soluble factors involved in cell/cell interactions and cloning of their genes are among the major accomplishments. Volumes I and II build on these developments in basic immunology to introduce animal models of various diseases, corresponding human studies, and the genetic analysis of autoimmune traits at the patient population level. The book will be a tremendous asset to immunologists, geneticists, and physicians in various areas of clinical subspecialties.

Table of Contents

Volume II:
Immunoglobulin and T Cell Redeptor Genes in SLE
Immunogenetics of Systemic Lupus Erythematosus
The Genetics of Systemic Lupus Erythematosus
The Immunogenetic Basis of Sjogren's Syndrome
Immunogenetics of Scleroderma and Mixed Connective Tissue Disease
Immunogenetics of Experimental Myasthenia Gravis: Contribution of IgVh Genes Encoding Anti-Dextran Antibodies to Immune Responsiveness Against the Acetylcholine Receptor
Immunogenetics of Type II Collagen-Induced Arthritis in Mice
Immunogenetics of Rheumatoid Arthritis and Ankylosing Spondylitis
Thyroid Autoimmunity in Experimental Models
Autoimmune Thyroid Disease
Immunogenetics of Type I Diabetes
Autoimmune Hepatitis and Other Diseases of the Liver: Immunogenetic Aspects
Immunogenetics of Pernicious Anemia
Immunogenetic Aspects of Inflammatory Bowel Disease
Immunogenetics of Multiple Sclerosis
Immuinogenetics of Autoimmune Renal Disease
Immunogenetics of Autoimmune Cutaneous Disease
Immunogenetics of Autoimmune Polyglandular Syndrome
Immunogenetics of AIDS
Index

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