1st Edition

The Immunology of Human Reproduction

By Isaac T. Manyonda Copyright 2006
    192 Pages
    by CRC Press

    190 Pages
    by CRC Press

    Understanding immunology is increasingly important in obstetrics and gynecology. Written primarily to meet the needs of practicing obstetricians and gynecologists, this book explores the role of immunological processes in reproduction. It presents immunologic concepts and illustrates important points with examples familiar to the clinician.

    The book is organized into four sections that explore the fundamentals of the immune system, the immunological paradox of pregnancy, clinical applications of immunology in obstetric and gynecologic practice, and immunopathology in obstetric and gynecologic practice. Written mainly for practicing obstetricians and gynecologists, the research results cited in the book are based on human experimentation.

    Fully illustrated with clear schematic drawings that highlight important concepts and processes, The Immunology of Human Reproduction gives readers an essential overview of immunology as it relates to human reproduction.

    Preface. FUNDAMENTALS OF THE IMMUNE SYSTEM. An Overview. Innate Immunity. B Cells and Antibodies. T Cells and Cytokines. MHC Molecules and Antigen Presentation. Lymphoid Organs and Immune Cell Trafficking. The Immune Response: Cellular and Humoral Interactions. THE IMMUNOLOGICAL PARADOX OF PREGNANCY. Historical Perspective - Metawat et al. Maternal Immunocompetence During Pregnancy. Maternal Immune Responses to the Fetus. How the Fetus Circumvents the Maternal Immune System. CLINICAL APPLICATIONS OF IMMUNOLOGY IN OBSTETRIC AND GYNAECOLOGIC PRACTICE. Rhesus Prophylaxis. Immunological Tests in Obstetrics and Gynaecology. Research. IMMUNOLOGY IN OBSTETRIC GYNAECOLOGIC PRACTICE. Recurrent Miscarriage - Immunological Aspects. Immunological Infertility and Contraception. Pre-Eclampsia. SLE and Other Connective Tissue Disorders in Pregnancy. Gynaecological Cancer and the Immune System.


    Manyonda, Isaac T.