The Kinesin Superfamily Handbook: Transporter, Creator, Destroyer, 1st Edition (Hardback) book cover

The Kinesin Superfamily Handbook

Transporter, Creator, Destroyer, 1st Edition

Edited by Claire Friel

CRC Press

192 pages | 10 Color Illus. | 25 B/W Illus.

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Hardback: 9781138589568
pub: 2020-05-22
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Description

This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for researchers looking to make comparisons between different families, for specific information on a family, or simply for an overview of the kinesin superfamily.

Information is clearly structured and grouped according to individual families and organized in a standardized way, allowing the reader to search and retrieve information on this large superfamily of molecular motors and understand how its individual members carry out a diverse variety of cellular functions.

Features:

  • The first book dedicated to the entire kinesin superfamily
  • Enables a fuller understanding of this family of proteins which is becoming an increasing focus of research due to its involvement in diseases such as cancer, neuropathies and ciliopathies.
  • Written in a manner accessible to a range of researchers in the life and medical sciences, including biophysicists, biochemists, and medical researchers.

Table of Contents

Chapter 1. The Kinesin Superfamily

Hannah R. Belsham & Claire T. Friel

Chapter 2. The Kinesin-1 family

David D. Hackney & Alison E. Twelvetrees

Chapter 3. The Kinesin-2 family - transporters

William O. Hancock

Chapter 4. The Kinesin-3 family – long distance cargo transporters

Nida Siddiqui & Anne Straube

Chapter 5. The Kinesin-4 family

Claire T. Friel

Chapter 6. The Kinesin-5 family: transporters and creators

Mary Popov, Alina Goldstein-Levitin & Larisa Gheber

Chapter 7. Kinesin-6

Claire T. Freil

Chapter 8. The Kinesin-8 family

Tianyang Liu, Alejandro Pena, Fiona Shilliday & Carolyn A. Moores

Chapter 9. The Kinesin-13 family – specialist destroyers

Julie P. Welburn & Claire T. Friel

Chapter 10. The Kinesin-14 family

Marcus Braun, Stefan Diez & Zdenek Lansky

Chapter 11. The Kinesin-15 family

Hauke Drechsler, Jaspreet Singh Grewal & Andrew D. McAnish

Chapter 12. The Kinesin-16 family

Hanan M. Alghamdi & Claire T. Freil

Chapter 13. Other Kinesin Families

Claire T. Friel

Chapter 14. Summary and Future Perspectives

Claire T. Friel

About the Editor

Claire Friel obtained a BSc in Biochemistry from the University of Glasgow and carried out her PhD work on protein folding kinetics in the laboratory of Sheena Radford at the University of Leeds. In 2006, worked at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden. During her time there, she solved the ATP turnover cycle of the microtubule depolymerising kinesin-13, MCAK, and developed a general interest in the kinesin superfamily of molecular motors. Since 2011, Claire has held the position of Assistant Professor at the University of Nottingham, where she oversees the Friel lab. The overarching research goal of the Friel lab is to understand the relationship between kinesin motor domain sequence and the many functional properties of the kinesin superfamily.

Subject Categories

BISAC Subject Codes/Headings:
MED008000
MEDICAL / Biochemistry
SCI017000
SCIENCE / Life Sciences / Cytology
SCI055000
SCIENCE / Physics