The Laboratory Canine: 1st Edition (Paperback) book cover

The Laboratory Canine

1st Edition

By Garrett Field, Todd A. Jackson

CRC Press

184 pages | 61 B/W Illus.

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pub: 2006-10-02
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Laboratory animals, including dogs, play an important role in biomedical research and medical advances. Dogs have a long history of use in research and have contributed enormously to the health and welfare of both humans and animals. The humane care and management of these animals is a fundamental component of their use in medical research.

The Laboratory Canine clearly presents basic background information covering subjects that apply specifically to dogs used in research settings, such as basic biological features, husbandry, management, veterinary care, experimental methodology, and resources. The book offers guidance on performing a detailed physical examination, including necessary veterinary supplies, clinical signs of illness, clinical conditions, and reference tables of widely used veterinary drugs. It discusses the human-animal bond or the relationship between people and animals and its significance and importance to the quality of research, the health of the animals, and the emotional health of staff caring for or working with animals.  It also examines anesthetic and surgical procedures that include pre-, intra-, and post-anesthesia/operative monitoring.  The Laboratory Canine contains reference charts for monitoring patients through post-operative recovery and reference tables for anesthetics and analgesics.

Because dogs are a highly visible species in the eyes of the public and regulators, it is important that individuals working with laboratory canines have the proper training and experience. This valuable resource is ideal for those charged with the care and use of canines in a research setting.


”The canine is one of the more highly regulated animal species because of its public image as a family member and the ever-present human-animal bond relationship. … Specific requirements concerning their housing, environmental enrichment, and proper medical management of pain and distress are outlined with references for additional in-depth information. … Attention is paid to human safety and zoootic diseases as well as the humane and ethical treatment of the animals themselves throughout the handbook. The Laboratory Canine is a valuable addition to the previously reviewed The Laboratory Animal Pocket Reference Series. It is an excellent reference for the individual wanting to strengthen their knowledge of basic canine care and guidelines in the laboratory setting. The handbook is conveniently sized and well written in an organized, easy to read manner, which will benefit the novice animal caretaker and laboratory assistant from small facilities to large institutions.”

—Sandra L. Jex, DVM, ALN Magazine, April 2007

“The intended audience of the book, The Laboratory Canine,is personnel involved with the care and use of dogs in research. The main target would be anima care staff and veterinary technicians. The book gives a general overview of the husbandry and care of research dogs, normal biological data for beagles, general disease conditions, basic anesthesia and common drug dosages, and sample collection methods. The book may be of interest to pathologists through the provision of these basic values and procedures … provide a very good technical reference for those in the field. The index is through, allowing quick access to information. …”

—Dr. Cecile Baccanale, DVM, Director of Animal Health, Marshall BioResources, New York, Veterinary Pathology, 2007

"The Laboratory Canine is a well and clearly written book and easy and pleasant to read."

– P. Rauser, in Acta Veternaria Brno, 2007, Vol. 76

"The book is clearly written and adequately referenced and touches on all aspects of care of laboratory dogs . . . an excellent quick reference source . . . "

– In AJVR, January 2008, Vol. 69, No. 1

Table of Contents


Origin of the Dog

Dog Breeds

Dog Behavior

Anatomic and Physiologic Features of Dogs

Normative Values of the Dog



Facility Design Considerations

Room Construction Features (Macroenvironment)

Outdoor Housing

Cage Materials and Design (Microenvironment)

Cage Size Standards

Environmental Conditions

Animal Care

Nutrition and Water

Environmental Enrichment

Exercise Requirements


Daily Schedule

Weekly Schedule

Semimonthly Schedule

Room Sanitation Schedule

Sanitation Quality Assurance Monitoring

Animal Receipt

Animal Identification


Record Keeping

Husbandry Records

Census Records

Medical Records


Regulatory Agencies and Compliance

U.S. Department of Agriculture

Public Health Service, National Institutes of Health, and

Office for Laboratory Animal Welfare

U.S. Food and Drug Administration and U.S. Environmental

Protection Agency Good Laboratory Practice Regulations

The Association for Assessment and Accreditation of

Laboratory Animal Care International

State and Local Agencies

Institutional Animal Care and Use Committee

Occupational Health and Safety




Intestinal Helminthes


Infections Resulting from Bite Wounds

Human-Animal Bond


Preventative Health Program


Quarantine, Stabilization, and Acclimation

Colony Separation

Clinical Management

Basic Veterinary Supplies

The Physical Examination

Clinical Signs of Illness in Dogs

Common Clinical Problems

Viral Diseases

Canine Parvovirus

Canine Distemper

Canine Coronavirus


Kennel Cough

Bacterial Diseases


Parasitic Diseases









Fungal Diseases

Miscellaneous Diseases and Conditions

Interdigital Cysts

Juvenile Polyarteritis Syndrome: Beagle Pain Syndrome

Cherry Eye

Dental Conditions


Implant Problems

Traumatic Injuries

Behavioral Disorders

Treatment of Diseases

General Treatment of Diarrhea

General Treatment of Dehydration

General Treatment of Anorexia

Drug Dosages in Dogs

Disease Prevention Through Sanitation

Anesthesia, Analgesia, and Sedation

Common Definitions

Principles of General Anesthesia

Stages of Anesthesia

Stage I: Voluntary Excitement

Stage II: Involuntary Excitement or Delirium

Stage III: Surgical Anesthesia

Stage IV: Medullary Paralysis and Respiratory Arrest

Assessment of the Depth of Anesthesia





Preanesthetic Management

Characteristics of Commonly Used Preanesthetics

Choosing an Anesthetic Regimen

Characteristics of Commonly Used Injectable Anesthetics

Principles of Gas Anesthesia

Characteristics of Commonly Used Gas Anesthetics

Principles of Local Anesthesia

Aseptic Surgery

Facilities, Features, and Equipment

Endotracheal Intubation


Preoperative Preparation

Operating Room Procedures

Postsurgical Management

Guidelines for the Assessment of Signs of Pain in Animals

Blood Donors


Signs of Morbidity (State of Disease or Illness) in Animals

Selected Criteria for Euthanasia of Moribund (State of Dying)



Canine Handling and Restraint

Mechanical Restraint Devices

Sample Collection Methods

Blood Collection

Urine Collection

Cerebrospinal Fluid Collection

Collection of Feces

Bone Marrow Collection

Test Article/Compound Administration Techniques

Formulation Guidelines

Volume Guidelines

Oral Dosing

Injection Sites

Implantable Osmotic Minipumps








Electronic Resources

Canine Sources

Transportation Services/Resources

Laboratory Services




Cages, Research, and Veterinary Supplies

Contact Information


About the Series

Laboratory Animal Pocket Reference

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
MEDICAL / Veterinary Medicine / General
MEDICAL / Research