1st Edition

The Metabolism of Arsenite

Edited By Joanne M. Santini, Seamus A. Ward Copyright 2012
218 Pages
by CRC Press

216 Pages
by CRC Press

218 Pages
by CRC Press

Up to 200 million people in 70 countries are at risk from drinking water contaminated with arsenic, which is a major cause of chronic debilitating illnesses and fatal cancers. Until recently little was known about the mobility of arsenic, and how redox transformations determined its movement into or out of water supplies. Although human activities contribute to the release of arsenic from... Read more

Arsenic in the environment
D. Kossoff & K.A. Hudson-Edward
Introduction
Chemistry and mineralogy of arsenic 
Distribution of arsenic in the environment 
Processes of arsenic cycling in the environment

Giant Mine,Yellowknife, Canada: Arsenite waste as the legacy of gold mining and processing
M. Bromstad & H.E. Jamieson
Introduction 
Background 
Arsenic and arsenite in mine wastes and surrounding area 
Transformation and remobilization of arsenic species 
Site remediation 
Summary

Genotoxic and carcinogenic risk of arsenic exposure. Influence of interindividual genetic variability
R. Marcos & A. Hernández
Introduction 
Carcinogenic risk 
Genotoxic risk 
Genetic polymorphisms affecting carcinogenic risk 
Genetic polymorphisms affecting genotoxic risk 
Conclusions

Overview of microbial arsenic metabolism and resistance
J.F. Stolz
Introduction 
Arsenic resistance 
Arsenic in energy generation

Prokaryotic aerobic oxidation of arsenite
T.H. Osborne & J.M. Santini
Introduction 
Aerobic arsenite-oxidizing bacteria 
Arsenite metabolism 
Aerobic arsenite-oxidizing communities 
Summary and future directions

Anaerobic oxidation of arsenite by autotrophic bacteria: The view from Mono Lake, California
R.S. Oremland, J.F. Stolz & C.W. Saltikov
Introduction 
Nitrate-respiring arsenite-oxidizers 
An annotated arsenate reductase that runs in reverse 
Anoxygenic photosynthesis fueled by arsenite

Arsenite oxidase
M.D. Heath, B. Schoepp-Cothenet, T.H. Osborne & J.M. Santini
Introduction 
Characteristics of the arsenite oxidase

Microbial arsenic response and metabolism in the genomics era
P.N. Bertin, L. Geist, D. Halter, S. Koechler, M. Marchal & F. Arsène-Ploetze
Introduction 
Descriptive and comparative genomics 
High-throughput genomics reveal the functioning of microorganisms 
Conclusions

Arsenite oxidation – regulation of gene expression
M.Wojnowska & S. Djordjevic 
Introduction 
Multiple modes of arsenite oxidase regulation 
AioSR and their involvement in Aio regulation 
Quorum sensing 
Heat-shock protein DNAJ 
Conclusions

Evolution of arsenite oxidation
R. van Lis,W. Nitschke, S. Duval & B. Schoepp-Cothenet
Introduction 
Molecular description of arsenic bioenergetic enzymes 
Function of the enzymes 
Phylogenetic analysis of Aio and Arr 
Taking bioenergetics into account 
Evolutionary scenario of arsenite oxidation

Remediation using arsenite-oxidizing bacteria
F. Delavat, M.-C. Lett & D. Lièvremont
Introduction
Arsenite oxidation-based remediation bioprocesses 
Conclusion

Development of biosensors for the detection of arsenic in drinking water
C. French, K. de Mora, N. Joshi, J. Haseloff & J. Ajioka 
Introduction 
Biosensors for detection of environmental toxins 
Biosensors for arsenic 
Conclusions

Subject index

Biography

Joanne M. Santini (University College London, UK) (Edited by) ,  Seamus A. Ward (University College London, UK) (Edited by)