1st Edition

The Neuroscience and Neuropsychology of Gambling

Edited By Luke Clarke, Anna E. Goudriaan Copyright 2022
    152 Pages
    by Routledge

    152 Pages
    by Routledge

    Gambling disorder is a behavioural addiction that represents the clinical extreme of a spectrum of gambling-related harm. What insights can neuroscientific and neuropsychological methods provide to help understand this condition and improve existing programs for treatment and prevention?

    This volume describes recent research using an array of contemporary tools including structural and functional brain imaging, and neurocognitive assessment. These analyses consider brain activity and psychological functioning in people with gambling disorder under resting conditions, due to tasks of reward processing and inhibitory control, and as a function of important sources of individual differences including depression and impulsivity. This volume also synthesizes contemporary research using animal models to examine decision-making under uncertainty from a behavioural neuroscience perspective, as well as synthesizing evidence from pharmacological treatments for gambling disorders. These findings complement research to understand substance use disorders and other emerging forms of behavioural addiction. This volume contains contributions from many of the leading research groups in this exciting field.

    The chapters in this book were originally published as a special issue of International Gambling Studies.

    1. Introduction: The neuroscience and neuropsychology of gambling and gambling addiction

    Luke Clark and Anna E. Goudriaan

    2. Negative interpersonal scenes decrease inhibitory control in healthy individuals but not in gambling disorder patients

    Anja Kräplin, Stefan Scherbaum, Gerhard Bühringer, Thomas Goschke and André Schmidt

    3. Regional grey matter volume correlates of gambling disorder, gamblingrelated cognitive distortions, and emotion-driven impulsivity

    Cristian M. Ruiz de Lara, Juan F. Navas, Carles Soriano-Mas, Guillaume Sescousse and José C. Perales

    4. The Rat Gambling Task as a model for the preclinical development of treatments for gambling disorder

    Patricia di Ciano and Bernard Le Foll

    5. Connectivity networks in gambling disorder: a resting-state fMRI study

    Tim van Timmeren, Paul Zhutovsky, Ruth J. van Holst and Anna E. Goudriaan

    6. Amygdala grey matter volume increase in gambling disorder with depression symptoms of clinical relevance: a voxel-based morphometry study

    Evangelos Zois, Falk Kiefer, Sabine Vollstädt-Klein, Tagrid Lemenager, Karl Mann and Mira Fauth-Bühler

    7. Relating neural processing of reward and loss prospect to risky decisionmaking in individuals with and without gambling disorder

    Iris M. Balodis, Jakob Linnet, Fiza Arshad, Patrick D. Worhunsky, Michael C. Stevens, Godfrey D. Pearlson and Marc N. Potenza

    8. A review of opioid-based treatments for gambling disorder: an examination of treatment outcomes, cravings, and individual differences

    Darren R. Christensen


    Luke Clark is Professor of Psychology at the University of British Columbia in Vancouver, Canada. His research on the psychology of gambling combines multiple methods including behavioural analysis, brain imaging, and psychophysiology. He has published over 200 peer-reviewed papers. He is Senior Editor at Addiction, and Regional Assistant Editor for International Gambling Studies.

    Anna E. Goudriaan is full Professor in Addiction: Mechanisms and Treatment at Arkin Mental Health Care and the Department of Psychiatry, Amsterdam University Medical Center, University of Amsterdam. She is a neuropsychologist and mental health psychologist with a combined research and clinical appointment. Her research focuses on the study of neurobiological mechanisms and innovative (neuromodulation) interventions in addictive disorders and dual diagnosis, including gambling disorder, alcohol use disorders and other substance use disorders (cannabis and cocaine). She has published over 120 peer-reviewed articles, book chapters and international papers.