The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.
Drug Delivery and Nanomedicine: A Primer for Physicians, Scientists, and Lawyers
What Is Precision Medicine? A Primer on Contemporary Issues and Concerns
Kadija Ferryman and Mikaela Pitcan
FDA’s Role in Paving the Way for Personalized Medicine
Multifunctional Gold Nanoparticles in Drug Delivery Systems
Zachary I. Stryker, Mehdi Rajabi, and Shaker A. Mousa
Nanoparticles and Nanoparticulate Drug Delivery Systems: Impact of Size and Structure on Functionality
Ajit S. Narang, Rong-Kun Chang, and Munir A. Hussain
Self-Assembling Peptide Amphiphiles as a Versatile Future Nanomedicine Platform
Run Chang and Thomas J. Webster
Pharmaceutical Applications of Water-Soluble Polymers in Nanomedicine and Drug Delivery
Schuyler A Pruyn et al.
Nanomaterials—Tools, Technology and Methodology of Nanotechnology Based Biomedical Systems for Diagnostics and Therapy
Christian Schmidt and Joachim Storsberg
Nano-Magnetic Resonance Imaging (Nano-MRI) Gives Personalized Medicine a New Perspective
Lorenzo Rosa, Jonathan Blackledge, and Albert Boretti
Advancing Precision Medicine: Tailoring Personalized Therapies
Kyle B. Matchett et al.
Precision Medicine for Alzheimer’s Disease Prevention
Cara L. Berkowitz et al.
Advanced Porphyrin Nanomaterials for Biological Applications
Haoyuan Huang and Jonathan F. Lovell
Cerium Oxide Nanoparticles as a Novel Reactive Oxygen Modulating Nanodrug
Ece Alpaslan and Thomas J. Webster
Artificial Nanomachines and Nanorobotics
Alexandre Loukanov, Hristo Gagov, and Seiichiro Nakabayashi
Translational Medicine at the Nanoscale: A Practical Guide
Raj Bawa and S. R. Bawa
Magneto-Responsive Scaffolds for Tissue Engineering Applications
Adedokun A. Adedoyin and Adam K. Ekenseair
Anticancer and Anti-Angiogenic Properties of Nano-Diamino-Tetrac, A Thyroid Hormone Derivative
Paul J. Davis and Shaker A. Mousa
Proteomic Profiling and Predictive Biomarkers in Neuro-Traumatology and Neuro-Oncology
Mario Ganau et al.
Nanomedicine and Personalized Care: Facts and Fiction
David M. Berube and Emily Winderman
Precision Immuno-Oncology: Prospects of Individualized Immunotherapy for Pancreatic Cancer
Jiajia Zhang, Christopher L. Wolfgang, and Lei Zheng
Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and Overtreatment
Vivek Podder et al.
Views from the FDA: Precision Medicine, Genetic Variant Databases and Companion Diagnostics
Use of Public Human Genetic Variant Databases to Support Clinical Validity for Genetic and Genomic-Based in vitro Diagnostics
Considerations for Design, Development, and Analytical Validation of Next Generation Sequencing (NGS) – Based in vitro Diagnostics (IVDs) Intended to Aid in the Diagnosis of Suspected Germline Diseases
Pharmacogenomics: Ethical, Legal, and Social Issues
Yann Joly and Denise Avard
From Single Level Analysis to Multi-Omics Integrative Approaches: A Powerful Strategy towards the Precision Oncology
Maria Eugenia Gallo Cantafio et al.
Harmonizing Outcomes for Genomic Medicine: Comparison of eMERGE Outcomes to ClinGen Outcome/Intervention Pairs
Janet L. Williams et al.
Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine
Fujimura et al.
Precision or Personalized Medicine for Cancer Chemotherapy: Is there a Role for Herbal Medicine
Zhijun Wang et al.
Personomics: The Missing Link in the Evolution from Precision Medicine to Personalized Medicine
Roy C. Ziegelstein
Stem Cell Banking for Regenerative and Personalized Medicine
David T. Harris