1st Edition

The Road from Nanomedicine to Precision Medicine Part B

Edited By Shaker A. Mousa, Raj Bawa, Gerald F. Audette Copyright 2019

    The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

    Drug Delivery and Nanomedicine: A Primer for Physicians, Scientists, and Lawyers

    Raj Bawa

    What Is Precision Medicine? A Primer on Contemporary Issues and Concerns

    Kadija Ferryman and Mikaela Pitcan

    FDA’s Role in Paving the Way for Personalized Medicine


    Multifunctional Gold Nanoparticles in Drug Delivery Systems

    Zachary I. Stryker, Mehdi Rajabi, and Shaker A. Mousa

    Nanoparticles and Nanoparticulate Drug Delivery Systems: Impact of Size and Structure on Functionality

    Ajit S. Narang, Rong-Kun Chang, and Munir A. Hussain

    Self-Assembling Peptide Amphiphiles as a Versatile Future Nanomedicine Platform

    Run Chang and Thomas J. Webster

    Pharmaceutical Applications of Water-Soluble Polymers in Nanomedicine and Drug Delivery

    Schuyler A Pruyn et al.

    Nanomaterials—Tools, Technology and Methodology of Nanotechnology Based Biomedical Systems for Diagnostics and Therapy

    Christian Schmidt and Joachim Storsberg

    Nano-Magnetic Resonance Imaging (Nano-MRI) Gives Personalized Medicine a New Perspective

    Lorenzo Rosa, Jonathan Blackledge, and Albert Boretti

    Advancing Precision Medicine: Tailoring Personalized Therapies

    Kyle B. Matchett et al.

    Precision Medicine for Alzheimer’s Disease Prevention

    Cara L. Berkowitz et al.

    Advanced Porphyrin Nanomaterials for Biological Applications

    Haoyuan Huang and Jonathan F. Lovell

    Cerium Oxide Nanoparticles as a Novel Reactive Oxygen Modulating Nanodrug

    Ece Alpaslan and Thomas J. Webster

    Artificial Nanomachines and Nanorobotics

    Alexandre Loukanov, Hristo Gagov, and Seiichiro Nakabayashi

    Translational Medicine at the Nanoscale: A Practical Guide

    Raj Bawa and S. R. Bawa

    Magneto-Responsive Scaffolds for Tissue Engineering Applications

    Adedokun A. Adedoyin and Adam K. Ekenseair

    Anticancer and Anti-Angiogenic Properties of Nano-Diamino-Tetrac, A Thyroid Hormone Derivative

    Paul J. Davis and Shaker A. Mousa

    Proteomic Profiling and Predictive Biomarkers in Neuro-Traumatology and Neuro-Oncology

    Mario Ganau et al.

    Nanomedicine and Personalized Care: Facts and Fiction

    David M. Berube and Emily Winderman

    Precision Immuno-Oncology: Prospects of Individualized Immunotherapy for Pancreatic Cancer

    Jiajia Zhang, Christopher L. Wolfgang, and Lei Zheng

    Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and Overtreatment

    Vivek Podder et al.

    Views from the FDA: Precision Medicine, Genetic Variant Databases and Companion Diagnostics


    Use of Public Human Genetic Variant Databases to Support Clinical Validity for Genetic and Genomic-Based in vitro Diagnostics


    Considerations for Design, Development, and Analytical Validation of Next Generation Sequencing (NGS) – Based in vitro Diagnostics (IVDs) Intended to Aid in the Diagnosis of Suspected Germline Diseases


    Pharmacogenomics: Ethical, Legal, and Social Issues

    Yann Joly and Denise Avard

    From Single Level Analysis to Multi-Omics Integrative Approaches: A Powerful Strategy towards the Precision Oncology

    Maria Eugenia Gallo Cantafio et al.

    Harmonizing Outcomes for Genomic Medicine: Comparison of eMERGE Outcomes to ClinGen Outcome/Intervention Pairs

    Janet L. Williams et al

    Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine

    Fujimura et al.

    Precision or Personalized Medicine for Cancer Chemotherapy: Is there a Role for Herbal Medicine

    Zhijun Wang et al

    Personomics: The Missing Link in the Evolution from Precision Medicine to Personalized Medicine

    Roy C. Ziegelstein

    Stem Cell Banking for Regenerative and Personalized Medicine

    David T. Harris


    Shaker A. Mousa, PhD is an endowed chair, tenured professor of Pharmacology at Albany College of Pharmacy; Vice Provost of Research, executive vice president, and chair of Pharmaceutical Research Institute at Albany, NY; president of Vascular Vision Pharmaceuticals; and founder of several spin-off pharmaceutical and biotechnology companies.

    Raj Bawa, MS, PhD, is president of Bawa Biotech LLC, a biotech/pharma consultancy and patent law firm based in Ashburn, VA, USA that he founded in 2002. He is an inventor, entrepreneur, professor and registered patent agent licensed to practice before the U.S. Patent & Trademark Office.

    Gerald F. Audette, PhD, is an Associate Professor in the Department of Chemistry and member of the Centre for Research on Biomolecular Interactions at York University in Toronto, Canada.