1st Edition

The Third Histamine Receptor Selective Ligands as Potential Therapeutic Agents in CNS Disorders

Edited By Divya Vohora Copyright 2009
406 Pages
by CRC Press

406 Pages
by CRC Press

400 Pages
by CRC Press

Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and Disorders The H 3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer’s disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic... Read more

INTRODUCTION. H3 Receptor Target: Past, Present, and Future Perspectives from Worldwide H3 Experts. The Third Histamine Receptor: From Discovery to Clinics, a Long- Lasting Love Story at INSERM and Bioprojet. Histamine as a Neurotransmitter. THE THIRD HISTAMINE RECEPTOR. Phylogeny, Gene Structure, Expression, and Signaling. Drug Discovery: From Hits to Clinical Candidates. Peripheral Actions and Therapeutic Potential in Periphery. THERAPEUTIC POTENTIAL IN CENTRAL NERVOUS SYSTEM DISORDERS. Cognitive Functions, Attention-Deficit Hyperactivity Disorders, and Alzheimer’s Disease. Sleep Disorders. Obesity. Epilepsy. Schizophrenia. Other Central Nervous System Disorders.

Biography

Vohora, Divya