This book provides a comprehensive, authoritative, and contemporary discussion of the physiology and pathophysiology of the chest wall as well as an overview of the diagnostic and therapeutic modalities. It is an invaluable aid to clinical investigators.
Table of Contents
Part I: Properties of Striated and Respiratory Muscles 1. Skeletal Muscle Physiology: Structure, Biomechanics, and Biochemistry 2. Electrophysiology and Excitation-Contraction Coupling in Skeletal Muscle 3. Pathophysiology of Skeletal Muscle 4. The Neuromuscular Junction 5. Structure and Function of the Respiratory Muscles 6. Fatigue of Striated Muscles: Metabolic Aspects 7. Changes in Activation, Contractile Speed, and Electrolyte Balance During Fatigue of Sustained and Repeated Contractions 8. Effects of Acid-Base Balance on Striated Muscles and the Diaphragm 9. Structural and Functional Adaptations of Skeletal Muscle 10. Effects of Aging on the Structure and Function of Skeletal Muscle 11. Cellular and Molecular Adaptations of the Respiratory Muscles 12. Oxygen-Derived Free Radicals and the Respiratory Muscles Part II: Respiratory Muscles: Mechanics and Energetics 13. An Abbreviated History of the Respiratory Muscles from Antiquity to the Classical Age 14. Functional Anatomy of the Chest Wall 15. The Act of Breathing 16. Statics of the Chest Wall 17. Dynamics of the Respiratory System 18. Kinematics of the Chest Wall 19. Actions of the Respiratory Muscles 20. Volume Displacements of the Chest Wall and Their Mechanical Significance 21. Topography of the Diaphragm 22. Chest Wall Mechanics in Newborns 23. Respiratory Muscle Blood Flow 24. Respiratory Muscle Metabolism 25. Respiratory Muscle Energetics Part III: Respiratory Muscle Control 26. Control of Respiratory Motor Activity 27. Organization and Recruitment of Diaphragm Motor Units 28. Reflex Influences Acting on the Respiratory Muscles of the Chest Wall 29. The Role of Small-Fiber Phrenic AITerents in the Control of Breathing 30. The Role of Myelinated AITerents from the Intercostal Muscles and Diaphragm 31. Functional Role of Respiratory Muscle Reflexes 32. Mechanical Aspects of Loaded Breathing 33. Reflex Compensation for Changes in Operational Length of Inspiratory Muscles 34. The Neuropharmacology of Central Fatigue in Respiratory Control Part IV: Methods of Measurement 35. Electrical Assessment of Respiratory Muscles 36. Noninvasive Methods for Measuring Ventilation 37. Rib Motion in Health and Disease 38. Pressures Developed by the Respiratory Muscles 39. Performance of Respiratory Muscles In Situ 40. Strength of Respiratory Muscles 41. Respiratory Muscle Endurance in Humans 42. Measurement of the Work of Breathing in the Critically Ill Patient 43. Assessment of Respiratory Sensation 44. Ultrasonography Part V: Specific Applications 45. Speech 46. Cough: Physiological and Pathophysiological Consideration 47. The Thorax in Exercise 48. Respiratory Muscle Activity During Sleep 49. Respiratory Muscle Fatigue 50. Inspiratory Pump Performance: A Pressure-Flow-Volume Framework 51. The Respiratory Muscles in Sepsis 52. Gravity 53. Chest Wall Mechanics in the Newborn 54. Respiration During Diving 55. Influence of Anesthesia on the Thorax 56. Thorax-Lung Interaction 57. Interaction Between the Circulatory and VentUatory Pumps 58. Cardiopulmonary Resuscitation 59. Dynamics of Breathing in Ventilatory Failure 60. Dyspnea Part VI: Diagnosis 61. Symptoms and Signs of Respiratory Muscle Dysfunction 62. Imaging of the Chest Wall and Diaphragm 63. Assessment of Thoracic Function 64. Respiratory Muscle Fatigue: Rationale for Diagnostic Test 65. Respiratory Muscle Pathology Part Vll: Pathophysiology 66. Thoracic Deformities 67. Obesity and Abdominal Distension 68. The Chest Wall and Respiratory Muscles in Chronic Obstructive Pulmonary Disease 69. The Respiratory System After Lung Transplantation 70. Thoracic Disorders in Childhood 71. Ventilatory Failure and Respiratory Muscles 72. Pleural, Alveolar, and Systemic Diseases Affecting Chest Wall Function 73. Neurological Disorders Affecting Respiration 74. The Respiratory System in Neuromuscular Disorders 75. Application of Cell and Molecular Biology to the Study of Respiratory 1951 1975 2007 2035 2071 2101 2135 2177 Muscle Adaptation and Disease 76. Respiratory Muscle Involvement in Systemic Autoimmune Diseases Part VIII: Therapeutic Approaches 77. Respiratory Muscle Rest 78. Coordination and Breathing Retraining 79. Conditioning of the Ventilatory Muscles 80. Respiratory Muscle Pharmacology 81. Interactions Between Patients and Ventilators 82. Ventilatory Support of Acute Respiratory Failure 83. The Role of PEEP or CPAP in the Mechanically Ventilated COPD Patient 84. Domiciliary Ventilation 85. Artificial Lung in Acute Respiratory Failure 86. Techniques of Constant Flow Ventilation 87. Respiratory Muscles and Rehabilitation 88. Phrenico-Diaphragmatic Pacing 89. Weaning 90. Nutrition and Respiratory Disease 91. Surgery of the Chest Wall