Theory and Practice of Contemporary Pharmaceutics  book cover
1st Edition

Theory and Practice of Contemporary Pharmaceutics

ISBN 9780415288637
Published November 23, 2004 by CRC Press
578 Pages 215 B/W Illustrations

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Book Description

With a shift toward problem-based learning and critical thinking in many health science fields, professional pharmacy training faces a shift in focus as well. Although the Accreditation Council for Pharmacy Education (ACPE) has recently suggested guidelines for problem solving to be better integrated into pharmacy curriculum, pharmacy books currently available either address this material inadequately or lack it completely. Theory and Practice of Contemporary Pharmaceutics addresses this problem by challenging pharmacy students to think critically in preparation for situations that arise in clinical practice.

This book offers a wealth of up-to-date information, organized in a logical sequence, corresponding to the art and science required for formulators in industry and dispensing pharmacists in the community. It breaks down the subject to its simplest form and includes numerous examples, case studies, and problems. In addition to presenting basic scientific principles, each chapter includes a self-evaluation tutorial designed to help you evaluate your understanding of the subject matter, numerical problems that provide practice in finding mathematical solutions, and case studies that measure your overall grasp of the subject matter by challenging you to craft a plausible solution to a real-life scenario using the concepts presented in that chapter.

Written by authors selected from academia, industry, and regulatory agencies, the book presents an objective and balanced view of pharmaceutical science and its application. The authors' insights are extremely helpful to pharmacy students as well as practicing pharmacists involved in the development and/or dispensation of existing and new generation biotechnology-based drug products. This simplified and user-friendly book will present pharmaceutics in a way that it has never been presented before and will help prepare students and pharmacists for the competitive and challenging nature of the professional market.

Table of Contents

Introduction: Methods of Data Representation, Interpretation, and Analysis; Craig Svensson, Tapash K. Ghosh

Thermodynamics and States of Matter; Adam M. Persky, Laszlo Prokai, Jeffrey A. Hughes

Solubility; Jeffrey A. Hughes, Adam M. Persky , Xin Guo, Tapash K. Ghosh

Physiochemical Factors Affecting Biological Activity; Blisse Jain, Surajit Dey, Hemant Alur, Bhaskara R. Jasti, Thomas P. Johnston, Ashim K. Mitra

Micromeritics and Rheology; Sunil S. Jambhekar

Principles and Applications of Surface Phenomena; Laszlo Prokai, Vien Nguyen, Bhaskara R. Jasti, Tapash K. Ghosh

Theory and Applications of Diffusion and Dissolution; Xiaoling Li, Bhaskara R. Jasti

Drug and Dosage Form Development: Regulatory Perspectives; Edward Dennis Bashaw

Chemical Kinetics and Stability; Tapash K. Ghosh

Oral Conventional Solid Dosage Forms: Powders and Granules, Tablets, Lozenges, and Capsules; Melgardt M. de Villiers

Oral Controlled Release Solid Dosage Forms; Emmanuel O. Akala

Oral Liquid Dosag Forms: Solutions, Elixirs, Syrups, Suspensions, and Emulsions; William M. Kolling, Tapash K. Ghosh

Parenteral Routes of Delivery; Yon Rojanasakul, Carl J. Malanga

Transdermal and Topical Drug Delivery Systems; Bhaskara R. Jasti, William Abraham, Tapash K. Ghosh

Rectal and Vaginal Routes of Drug Delivery; Nikhil R. Shitut, Sumeet K. Rastogi, Somnath Singh, Feirong Kang, Jagdish Singh

Ocular, Nasal, Pulmonary, and Otic Routes of Drug Delivery; Harisha Atluri, Giridhar, S. Tirucherai, Clapton Dias, Jignesh Patel, Ashim K. Mitra

Delivery of Peptide and Protein Drugs; Emily Ha, Manjori Ganguly, Xiaoling Li, Bhaskara R. Jasti, Uday B. Kompella


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Tapash K. Ghosh, Ph.D., is employed by the Office of Clinical Pharmacology and Biopharmaceutics at CDER, FDA. Before joining the FDA, he held faculty positions in the division of pharmaceutical sciences at the Massachusetts College of Pharmacy in Boston and Howard University in Washington, DC. He also worked in various pharmaceutical industries. He is the author of numerous scientific publications and the principal editor of other scientific books.

Bhaskara R. Jasti, Ph.D., is an associate professor in the Department of Pharmaceutics and Medicinal Chemistry, TJL School of Pharmacy, University of the Pacific. Dr. Jasti teaches an integrated curriculum covering basic pharmaceutics and biopharmaceutics courses at the University of the Pacific. Following Ph.D. and postdoctoral training, Dr. Jasti’s first academic appointment was at Wayne State University in the Departments of Pharmacy and Internal Medicine. His current research interests are identifying the barriers for drug delivery and targeted delivery of drugs to cancer cells. Dr. Jasti has published more than 30 papers and presented more than 50 papers at various national and international meetings.


"The authors have a wealth of both industry and academic experience making this a well organized book. … [It] presents the subject matter in a logical fashion. The problems at the end of each chapter help students reinforce newly learned concepts and serve as a valuable learning tool. The book accomplishes its goal by providing thorough coverage of the material."
- Doody's Review