Thyroid Cancer: From Emergent Biotechnologies to Clinical Practice Guidelines (Hardback) book cover

Thyroid Cancer

From Emergent Biotechnologies to Clinical Practice Guidelines

Edited by Angelo Carpi, Jeffrey I Mechanick

© 2011 – CRC Press

408 pages | 12 Color Illus. | 84 B/W Illus.

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Hardback: 9781439862216
pub: 2011-05-24
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The current age of clinical medicine is witnessing biotechnological innovation at an unprecedented pace. As a result, the recently popularized clinical practice guidelines (CPG), as a tool to assist clinical decision-making, have been struggling to keep up. Thyroid Cancer: From Emergent Biotechnology to Clinical Practice Guidelines rides the wave of medical innovation, analyzing current and future CPG, and providing an up-to-date and comprehensive treatise on thyroid cancer, its diagnosis, and treatment.

A synthesis of ideas by prominent world experts in the field of thyroid cancer research and clinical practice, Thyroid Cancer covers:

  • Technologically-advanced diagnostic procedures and therapeutic interventions
  • Diagnostic techniques employed in the detection and follow-up of thyroid cancer including ultrasound, needle aspiration techniques, CT, PET, PET-CT, and MRI
  • Basic principles of systems biology, molecular and translational medicine, CPG development, and risk stratification for thyroid cancer
  • How CPG contain knowledge gaps and produce uncertainty
  • Advances in the field, including new surgical techniques, molecular targeted therapies, external beam radiation therapy, and chemotherapy

A comprehensive, scientific description of current and future diagnostic and therapeutic modalities for the management of thyroid cancer, this treatise is an indispensible reference for both the specialist and referring physician.

Table of Contents

Principles of Translational Medicine and Applications to Thyroid Cancer Investigation

Emily Jane Gallagher and Derek LeRoith

Systems Biology—An Overview

Ravi Iyengar and Azi Lipshtat

Genetic and Epigenetic Alterations in the MAP Kinase and PI3K/Akt Pathways in Thyroid Cancer

Mingzhao Xing and Paul W. Ladenson

Genetic and Molecular Pathophysiology of Medullary Thyroid Carcinoma

Rosa Maria Paragliola, Salvatore M. Corsello, Francesco Torino, and Agnese Barnabei

Risk Stratification in Differentiated Thyroid Cancer

Giuseppe Barbesino

Clinical Practice Guidelines for Thyroid Cancer: Where Are We Now?

Jeffrey I. Mechanick

Illustrative Case Studies of Thyroid Carcinoma and the Emerging Role of Molecular Medicine

Donald Bergman and Rhoda H. Cobin

Advances in Thyroid Ultrasound for Detection and Follow-Up of Thyroid Malignancies: Technical and Clinical Aspects

Laurence Leenhardt, François Tranquart, and Jean Tramalloni

Multimodality Imaging and Aspiration Biopsy Guidance in the Perioperative Management of Thyroid Carcinoma

Jing Gao, Jonathan K. Kazam, and Elias Kazam

The Use of Diagnostic Radiotracers in Thyroid Cancer

Josef Machac

PET-CT Scanning in the Management of Thyroid Cancer: Experience with a Cohort of 100 Patients

Dario Casara, Faise Al Bunni, Maria Rosa Pelizzo, and Fabio Pomerri

The Emerging Role of Percutaneous Needle Biopsy and Molecular Tumor Marker Analysis for the Preoperative Selection of Thyroid Nodules

Angelo Carpi, Jeffrey I. Mechanick, and Andrea Nicolini

Image-Guided Mini-Invasive Ablation of Thyroid Tumors and Distant Metastases

Enrico Papini, Antonio Bianchini, Rinaldo Guglielmi, Claudio M. Pacella,Irene Misischi, Laura Papini, and Giancarlo Bizzarri

Thyroidectomy and Neck Exploration: New Surgical Approaches

Jean-Christophe Lifante and William B. Inabnet III

Thyroid Surgery Performed under Local Anesthesia and Same-Day Surgery

Joseph DiNorcia and John D. Allendorf

The Use of Therapeutic Radiotracers in Thyroid Cancer

Josef Machac

External Beam Radiation Therapy in Thyroid Cancer

Walter Choi and Louis Harrison

Role of Chemotherapy in Thyroid Cancer

Paolo Bossi and Laura D. Locati

Role of NF-κB in Thyroid Cancer

Eriko Suzuki, Shunichi Yamashita, and Kazuo Umezawa

Biologically Targeted Therapies for Thyroid Cancers

Steven I. Sherman

Molecular Targeted Therapies of Medullary Thyroid Carcinoma

Francesco Torino, Agnese Barnabei, Rosa Maria Paragliola, and Salvatore M. Corsello

Synthesis of Emergent Biotechnologies into Future CPG

Jeffrey I. Mechanick, Angelo Carpi, Mark Urken, Donald Bergman, and Rhoda H. Cobin

About the Editors

Angelo Carpi, MD is a clinical researcher at the University Hospital of Pisa. He is also an associate professor of Internal Medicine at Pisa University.

Jeffrey I. Mechanick, MD, Mount Sinai School of Medicine, New York City, is a Clinical Professor within the Department of Medicine, Division of Endocrinology, Diabetes, and Bone Disease at the Mount Sinai School of Medicine.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Endocrinology & Metabolism
MEDICAL / Oncology
SCIENCE / Life Sciences / Biology / Molecular Biology