Tissue Engineering: Principles and Practices, 1st Edition (Paperback) book cover

Tissue Engineering

Principles and Practices, 1st Edition

Edited by John P. Fisher, Antonios G. Mikos, Joseph D. Bronzino, Donald R. Peterson

CRC Press

771 pages | 130 B/W Illus.

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Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the field into a broad context, Tissue Engineering: Principles and Practices explores current thoughts on the development of engineered tissues.

With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. A comprehensive overview of major research topics in tissue engineering, the book:

  • Examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue-engineered devices
  • Focuses upon those strategies typically incorporated into tissue-engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques
  • Presents synthetic tissues and organs that are currently under development for regenerative medicine applications

The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, this book includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue-engineered devices. The book provides a useful reference for courses devoted to tissue engineering fundamentals and those laboratories developing tissue-engineered devices for regenerative medicine therapy.

Table of Contents


Strategic Directions, Peter C. Johnson

Silks, Monica A. Serban and David L. Kaplan

Calcium Phosphates, Kemal Sariibrahimoglu, Joop G.C. Wolke, Sander C.G. Leeuwenburgh, and John A. Jansen

Engineered Protein Biomaterials, Andreina Parisi-Amon and Sarah C. Heilshorn

Synthetic Biomaterials, Joshua S. Katz and Jason A. Burdick

Growth Factors and Morphogens: Signals for Tissue Engineering, A. Hari Reddi

Signal Expression, Martha O. Wang and John P. Fisher

Pluripotent Stem Cells, Todd C. McDevitt and Mellissa A. Kinney

Hematopoietic Stem Cells, Ian M. Kaplan, Sebastien Morisot, and Curt I. Civin

Mesenchymal Stem Cells, Pamela C. Yelick and Weibo Zhang

Enabling Technologies

Nanobiomaterials for Tissue Engineering, Pramod K. Avti, Sunny C. Patel, Pushpinder Uppal, Grace O’Malley, Joseph Garlow, and Balaji Sitharaman

Biomimetic Approaches in Tissue Engineering, Indong Jun, Min Sup Kim, Ji-Hye Lee, Young Min Shin, and Heungsoo Shin

Molecular Biology Techniques, X.G. Chen, Y.L. Fang, and W.T. Godbey

Biomaterial Mechanics, Kimberly M. Stroka, Leann L. Norman, and Helim Aranda-Espinoza

Mechanical Conditioning, Elaine L. Lee and Horst A. von Recum

Micropatterned Biomaterials for Cell and Tissue Engineering, Murugan Ramalingam and Ali Khademhosseini

Drug Delivery, Prinda Wanakule and Krishnendu Roy

Gene Therapy, Abhay Pandit, C. Holladay, M. Kulkarni, and W. Minor

Nanotechnology-Based Cell Engineering Strategies for Tissue Engineering and Regenerative Medicine Applications, Joaquim Miguel Oliveira, João Filipe Mano, and Rui Luís Reis

Cell Encapsulation, Stephanie J. Bryant

Coculture Systems for Mesenchymal Stem Cells, Song P. Seto and Johnna S. Temenoff

Tissue Engineering Bioreactors, Sarindr Bhumiratana, Elisa Cimetta, Nina Tandon, Warren Grayson, Milica Radisic, and Gordana Vunjak-Novakovic

Shear Forces, Jose F. Alvarez-Barreto, Samuel B. VanGordon, Brandon W. Engebretson, and Vasillios I. Sikavitsas

Vascularization of Engineered Tissues, Monica L. Moya and Eric M. Brey

Biomedical Imaging of Engineered Tissues, Nicholas E. Simpson and Athanassios Sambanis

Multiscale Modeling of In Vitro Tissue Cultivation, Kyriacos Zygourakis


Bone Engineering, Lucas A. Kinard, Antonios G. Mikos, and F. Kurtis Kasper

Dental and Craniofacial Bioengineering, Hemin Nie and Jeremy J. Mao

Tendon and Ligament Engineering, Nicholas Sears, Tyler Touchet, Hugh Benhardt, and Elizabeth Cosgriff-Hernández

Cartilage Tissue Engineering, Emily E. Coates and John P. Fisher

TMJ Engineering, Michael S. Detamore

Interface Tissue Engineering, Helen H. Lu, Nora Khanarian, Kristen Moffat, and Siddarth Subramony

The Bioengineering of Dental Tissues, Rena N. D’Souza, Katherine R. Regan, Kerstin M. Galler, and Songtao Shi

Tissue Engineering of the Urogenital System, In Kap Ko, Anthony Atala, and James J. Yoo

Vascular Tissue Engineering, Laura J. Suggs

Neural Engineering, Yen-Chih Lin and Kacey G. Marra

Tumor Engineering: Applications for Cancer Biology and Drug Development, Joseph A. Ludwig and Emily Burdett


Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology