Tissue Engineering: 1st Edition (Hardback) book cover

Tissue Engineering

1st Edition

By John P. Fisher, Antonios G. Mikos, Joseph D. Bronzino

CRC Press

600 pages | 137 B/W Illus.

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Hardback: 9780849390265
pub: 2007-05-30
eBook (VitalSource) : 9780429124440
pub: 2007-05-30
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Increasingly viewed as the future of medicine, the field of tissue engineering is still in its infancy. As evidenced in both the scientific and popular press, there exists considerable excitement surrounding the strategy of regenerative medicine. To achieve its highest potential, a series of technological advances must be made. Putting the numerous breakthroughs made in this field into a broad context, Tissue Engineering disseminates current thinking on the development of engineered tissues.

Divided into three sections, the book covers the fundamentals of tissue engineering, enabling technologies, and tissue engineering applications. It examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue engineered devices. Contributions focus on those strategies typically incorporated into tissue engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques. Finally, the book presents synthetic tissues and organs that are currently under development for regenerative medicine applications.

The ability to engineer biocompatible tissue is the hallmark of modern biomedical engineering, integrating all aspects of every sub-discipline in the field. Featuring chapters drawn from the third edition of the best-selling Handbook of Biomedical Engineering as well as new contributions not found in the handbook, Tissue Engineering surveys the latest advances in this relatively young area. The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, the text includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue engineered devices.

Table of Contents

Fundamentals of Tissue Engineering

Fundamentals of Stem Cell Tissue Engineering, A.I. Caplan

Growth Factors and Morphogens:Signals for Tissue Engineering, A.H. Reddi

Extracellular Matrix: Structure, Function, and Applications to Tissue Engineering M.C. Farach-Carson, R.C. Wagner, and K.L. Kiick

Mechanical Forces on Cells, Y.-T. Shiu

Cell Adhesion, A.S. Goldstein

Cell Migration, G. Cheng and K. Zygourakis

Inflammatory and Immune Responses to Tissue Engineered Devices, J.M. Anderson

Enabling Technologies

Polymeric Scaffolds for Tissue Engineering Applications, D.M. Yoon and J.P. Fisher

Calcium Phosphate Ceramics for Bone Tissue Engineering, P.Q. Ruhé, J.G.C. Wolke, P.H.M. Spauwen, and J.A. Jansen

Biomimetic Materials, A.J. García

Nanocomposite Scaffolds for Tissue Engineering, A.S. Mistry, X. Shi, and A.G. Mikos

Roles of Thermodynamic State and Molecular Mobility in Biopreservation, A. Aksan and M. Toner

Drug Delivery, C. Becker and A. Göpferich

Gene Therapy, J.M. Munson and W.T. Godbey

Tissue Engineering Bioreactors, J.F. Alvarez-Barreto and V.I. Sikavitsas

Animal Models for Evaluation of Tissue-Engineered Orthopedic Implants, L. Lu, E. Jabbari, M.J. Moore, and M.J. Yaszemski

The Regulation of Engineered Tissues: Emerging Approaches, K.B. Hellman and D. Smith

Tissue Engineering Applications

Bioengineering of Human Skin Substitutes, D.M. Supp and S.T. Boyce

Nerve Regeneration: Tissue Engineering Strategies, J.B. Recknor and S.K. Mallapragada

Gene Therapy and Tissue Engineering Based on Muscle-Derived Stem Cells: Potential for Musculoskeletal Tissue Regeneration and Repair, J. Huard, B. Cao, Y. Li, and H. Peng

Tissue Engineering Applications —Bone, A.B. Celil, S. Guelcher, J.O. Hollinger, and M. Miller

Cartilage Tissue Engineering, F. Yang and J.H. Elisseeff

Tissue Engineering of the Temporomandibular Joint, M.E.K. Wong, K.A. Athanasiou, and K.D. Allen

Engineering Smooth Muscle, Y. Ching Yung and D.J. Mooney

Esophagus: A Tissue Engineering Challenge, B.D. Ratner, B.L. Beckstead, K.S. Chian, and A.C. Ritchie

Tissue Engineered Vascular Grafts, R.H. Schmedlen, W.M. Elbjeirami, A.S. Gobin, and J.L. West

Cardiac Tissue Engineering: Matching Native Architecture and Function to Develop Safe and Efficient Therapy, N. Bursac

Tissue Engineering of Heart Valves, K.J. Grande-Allen

Tissue Engineering, Stem Cells and Cloning for the Regeneration of Urologic Organs, J.D. Rackley and A. Atala

Hepatic Tissue Engineering for Adjunct and Temporary Liver Support, F. Berthiaume, A.W. Tilles, M. Toner, M.L. Yarmush, and C. Chan

Tissue Engineering of Renal Replacement Therapy, W.H. Fissell and H.D. Humes

The Bioengineering of Dental Tissues, R.N.D ’Souza and S. Shi

Tracheal Tissue Engineering, B. Dunham, P. Flint, S. Singhal, C. Le Visage, and K. Leong

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology