Toxicological Testing Handbook: Principles, Applications and Data Interpretation, 2nd Edition (Paperback) book cover

Toxicological Testing Handbook

Principles, Applications and Data Interpretation, 2nd Edition

Edited by David Jacobson-Kram, Kit A. Keller

CRC Press

499 pages

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Description

Furnishing essential data on all areas of toxicity testing, this Second Edition provides guidance on the design and evaluation of product safety studies to help ensure regulatory acceptance.  Every chapter highlights regulatory requirements specific to the United States, Europe, and Japan, and in addition to expanded information on data interpretation, hazard assessment, carcinogenicity studies, and Good Laboratory Practices, new chapters regarding safety pharmacology, juvenile studies, the health safety assessment of pharmaceuticals, and health assessment strategies in the food and cosmetic industry have been added to reflect changes to regulatory requirements.  Toxicological Testing Handbook, Second Edition is a must-have reference for individuals responsible for assuring the safety of new pharmaceutical, biotechnical, and chemical products and materials.

Table of Contents

Regulatory Toxicology Testing: Laboratories and Good Laboratory Practices.  Laboratory Animals and In Vitro Test Systems Used in Regulatory Toxicology.  Metabolism and Toxicokinetics.  Toxicologic Pathology Assessment.  Acute Toxicology.  Multidose General Toxicology Studies.  Genetic Toxicology.  Carcinogenicity Studies.  Juvenile Animal Toxicology Studies.  Developmental and Reproductive Toxicology.  Neurotoxicology Testing.  Toxicological Assessment of the Immune System.  Inhalation and Pulmonary Toxicity Studies.  Cancer Risk Assessment.  Nonclinical Safety Testing of Pharmaceuticals.  Health Risk Assessment Strategies in the Food and Cosmetic Industry.

About the Editors

David Jacobson-Kram, Kit A. Keller

Subject Categories

BISAC Subject Codes/Headings:
MED000000
MEDICAL / General
MED071000
MEDICAL / Pharmacology
MED096000
MEDICAL / Toxicology