Toxicology of the Kidney  book cover
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3rd Edition

Toxicology of the Kidney





ISBN 9780367393403
Published October 22, 2019 by CRC Press
1200 Pages

 
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Book Description

The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy, biochemistry, and physiology of the kidney.

The text explains how these factors are related to concepts of clinical nephrotoxicity and renal failure in humans, and how animal models can be used to understand the mechanisms of human renal disease. In addition to updating many of the key elements of previous editions, such as in vitro models for studying renal function and toxicity and classic nephrotoxicants, it also incorporates cutting edge information on newly emerging areas of renal research. These include mechanisms of cell injury, signaling pathways, biomarkers of renal disease and the interface between basic renal science and clinical outcomes.

This book includes current reviews of unpublished and recently published information which allows it to serve as a concise compendium of many key topics that will continue to play a central role in our understanding and treatment of nephrotoxicity for decades to come.

Table of Contents

Basic Principles. Mechanisms of NephrotoxicityClinical Nephrotoxicity and Specific Classes of Nephrotoxicants. Risk/Safety Assessment.

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Editor(s)

Biography

Joan B. Tarlofr, Lawrence H. Lash