Translational Medicine The Future of Therapy?
This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM) to significantly enhance conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure/resources. In recognition of the various implications TM has for public health policy and commercial innovation, this cutting-edge, interdisciplinary book addresses the major systemic aspects of the field.
Introduction to Translational Medicine
James Mittra and Christopher-Paul Milne
Drivers and Barriers to Translational Medicine
New Light Through an Old Window? The "Translational Turn" in Biomedical Research — A Historical Perspective
Translational Medicine: The Industry Perspective
Christopher-Paul Milne, Christine Kohn
Drivers and Barriers of Translational Medicine: A Regulatory Perspective
Partha Roy, Atul Bhattaram, and Shiew Mei Huang
Developing an Evaluation Model for Translational Medicine Research Programs
State of the Art in Science and Technology
Emerging Concepts in Biomarker Discovery: Cancer Immunotherapy and Degenerative Diseases of the Eye as Model Systems
Robert B. Nussenblatt, and Francesco M. Marincola
Imaging Biomarkers for Innovative Drug Development: Translation from Bench to Bedside and Back
Translational Bioinformatics: Bridging the Biological and Clinical Divide
Indra Neil Sarkar
Institutional Dynamics of Translational Medicine
Exploiting Translational Medicine Through Public–Private Partnerships: A Case Study of Scotland’s Translational Medicine Research Collaboration (TMRC)
The Role of the Product Development Partnership as a Translational Mechanism for Delivering Health Solutions in Low-Resource Settings
Julius Mugwagwa, Rebecca Hanlin, Joanna Chataway, and Lois Muraguri
Is Translational Medicine the Future of Therapy?
Christopher-Paul Milne and James Mittra
"This is a book that should be read by all those aiming to improve the efficiency and effectiveness of translation of science into clinical practice and health outcomes. Unlike other contributions in the field, it takes a holistic approach to the problem and recognises the dynamic nature of demand for as well as supply of health innovation, identifying strategies to integrate the two. This book has been needed for some time, but, with stagnating productivity and ever-increasing economic pressures, never more so than right now."
—Prof. Iain Gillespie, The University of Edinburgh, UK