Traumatic Brain Injury : Rehabilitation, Treatment, and Case Management, Fourth Edition book cover
4th Edition

Traumatic Brain Injury
Rehabilitation, Treatment, and Case Management, Fourth Edition

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ISBN 9781498710299
Published August 17, 2017 by CRC Press
784 Pages 110 B/W Illustrations

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Book Description

The fourth edition of this text constitutes a continuation of 20 years of coverage of traumatic brain injury, and broadens the discussion of acquired brain injury. Within TBI, the paradigm shift from an injury occurring at a point in time to a disease entity of a chronic nature is changing the discussion of diagnosis, management, treatment and outcome assessment. Disease specification that differentiates TBIs by the mechanism of injury, the exact nature of the injury, the extent of injury, presence of co-morbidities and their exact nature, gender, age, race, and genome are emerging as crucial. Disease differentiation has impacted diagnosis, treatment and outcome.

Table of Contents



  1. Bioscience Indications for Chronic Disease Management and Neuromedical Interventions Following Traumatic Brain Injury
  2. – Mark J. Ashley, Grace S. Griesbach, David L. Ripley, Matthew J. Ashley

  3. The Neurobiology of Traumatic Brain Injury
  4. – Thomas C. Glen, Richard L. Sutton and David A. Hovda

  5. Repeat Traumatic Brain Injury Models
  6. – Mayumi Prins

  7. Neuroplasticity and Rehabilitation Therapy
  8. – Robert P. Lehr

  9. Environment Enrichment: A Preclinical Model of Neurorehabilitation for Traumatic Brain Injury
  10. – Corina O. Bondi & Anthony E. Kline

  11. Neuroanatomy of Basic Cognitive Function
  12. – Mark J. Ashley, Jessica G. Ashley & Matthew J. Ashley

  13. TBI Rehabilitation: Lessons Learned from Animal Studies about Mechanisms, Timing and Combinatorial Approaches
  14. – Dorothy A. Kozlowski

  15. Diet and Exercise Interventions to Promote Metabolic Homeostasis in TBI Pathology
  16. – Fernando Gomez-Pinilla

  17. Disruptions in Physical Substrates of Vision Following Traumatic Brain Injury
  18. – Richard E. Helvie

  19. Potential Utility of Resting State fMRI-Determined Functional Connectivity to Guide Neurorehabilitation
  20. – Neil G. Harris and Jessica G. Ashley

  21. TBI and Sensory Sensitivity: Translational Opportunities
  22. – Timothy W. Ellis and Jonathan Lifshitz

  23. The Neuroimaging Challenges in Hemispherectomy Patients
  24. – Zachary Jacokes, Avnish Bhattrai, Carinna Torgerson, Andrew Zywiec, Sumiko Abe, Andrei Irimia, Meng Law, Saman Hazany, and John Darrell Van Horn



  25. Clinical Management of the Minimally Conscious State
  26. – Yelena G. Bodien, Sabrina R. Taylor, and Joseph T. Giacino

  27. Neuropharmacologic Considerations in the Treatment of Vegetative State and Minimally Conscious State Following Brain Injury
  28. – Deborah L. Doherty

  29. Clinical Management of Pituitary Dysfunction After Traumatic Brain Injury – Adam H. Maghrabi, Brent E. Masel, Randall J. Urban, and David L. Ripley
  30. Neurotransmitters and Pharmacology
  31. – Ronald A. Browning and Richard W. Clough

  32. Pituitary Dysfunction After Traumatic Brain Injury – Tiffany Greco
  33. Increasing Physiologic Readiness to Improve Functional Independence Following Neurotrauma
  34. –Gregory J. O’Shanick and Ryan McQueen

  35. Assessment and Management of Mild Traumatic Brain Injury
  36. – Mark J. Ashley, Matthew J. Ashley

  37. Chronic Traumatic Encephalopathy (CTE)
  38. – Anne C. McKee

  39. Posttraumatic Epilepsy and Neurorehabilitation
  40. – Theresa D. Hernández, Sudha S. Tallavajhula, Kristina Legget, and Paul M. Levisohn



  41. Evaluation of Traumatic Brain Injury Following Acute Rehabilitation
  42. – Mark J. Ashley

  43. Neuropsychology following Brain Injury: A Pragmatic Approach to Outcomes, Treatment, and Applications- James J. Mahoney, III
  44. Neuropsychological Interventions Following Traumatic Brain Injury
  45. – Jason W. Krellman, TheodoreTsaousides, and Wayne A. Gordon

  46. The Use of Applied Behavioral Analysis in Traumatic Brain Injury Rehabilitation
  47. – Craig S. Persel and Chris H. Persel

  48. Rehabilitation and Management of Visual Dysfunction Following Traumatic Brain Injury
  49. – Penelope S. Suter

  50. Remediative Approaches for Cognitive Disorders After TBI
  51. – Mark J. Ashley, Rose Leal, Zenobia Mehta, Jessica G. Ashley, Matthew J. Ashley

  52. Principles of Cognitive Rehabilitation in TBI: An Integrative Neuroscience Approach
  53. – Fofi Constantinidou and Robin D. Thomas

  54. Management of Residual Physical Deficits
  55. – Velda L. Bryan, David W. Harrington, Michael G. Elliott

  56. Undertaking Vocational Rehabilitation in TBI Rehabilitation
  57. – Mark J. Ashley, Joe Ninomiya, Jr., Amy Berryman, Karen Rasavage



  58. The Contribution of Neuropsychological Evaluation to Traumatic Brain Injury Rehabilitation
  59. – Jay M. Uomoto

  60. Neurobehavioral Consequences of Mild Traumatic Brain Injury in Military Service Members and Veterans
  61. – Jay M. Uomoto, Sarah M. Wilson, Rhonda M. Williams, and Leigh A. Randa

  62. Issues in Aging Following Traumatic Brain Injury
  63. – Grace S. Griesbach, Mark J. Ashley, Alan Weintraub

  64. Children and Adolescents: Practical Strategies for School Participation and Transition
  65. – Roberta DePompei and Janet Siantz Tyler

  66. Long-Term Discharge Planning in Traumatic Brain Injury Rehabilitation
  67. – Mark J. Ashley and Susan M. Ashley

  68. Patients’ Rights and Responsibilities, Health Care Reform and Telehealth: Ethical Considerations

– Thomas R. Kerkhoff and Stephanie L. Hanson




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Dr. Mark J. Ashley is founder and president/CEO of Centre for Neuro Skills (CNS), which has operated postacute brain injury rehabilitation programs in Bakersfield, Los Angeles, Dallas, Fort Worth, and San Francisco since 1980. In 2011, Dr. Ashley participated in the Blue Ribbon Panel on Traumatic Brain Injury and Post-Traumatic Stress convened by Generals Peter W. Chiarelli and Joseph Dunford, and he established the CNS Clinical Research and Education Foundation, a nonprofit research organization. He serves on the board of directors of the Brain Injury Association of America (BIAA) and holds several positions in that organization, including chairman emeritus, chair of the fund development committee, and member of the Business and Professional Council. Dr. Ashley also serves on the board of directors of the California Brain Injury Association and is chairman emeritus. He is an adjunct professor at the Rehabilitation Institute of the College of Education at Southern Illinois University and a member of the advisory board of the Center for Applied Neuroscience, University of Cyprus. Dr. Ashley received his master’s degree in speech pathology and a doctorate of science from Southern Illinois University in Carbondale, Illinois. He is a licensed speech-language pathologist in California and Texas and is a certified case manager.

Dr. David A. Hovda is the director of the UCLA Brain Injury Research Center, which was created in 1990. It incorporates teaching, research, patient care, and service for patients suffering from traumatic brain injury. Dr. Hovda has received a number of awards for his research on brain injury and recovery of function, including the "Strength of the Nation Award" from the United States Army in 2011. This is the highest civilian award given by the Secretary of the Army in recognition of Dr. Hovda’s efforts to help treat military personnel suffering from mild traumatic brain injury returning from theater. In addition, Dr. Hovda received the Alumni Association’s James F. Zimmerman Award from the University of New Mexico in 2012 for his research accomplishments recognized in the field of traumatic brain injury. Dr. Hovda is most well known internationally for his translational work on the pathobiology of traumatic brain injury and has devoted most of his career to understanding the mechanisms of recovery of function. Dr. Hovda continues to serve as a consultant for professional sport organizations as well as the Department of Defense, addressing issues related to traumatic brain injury and recovery of function. Dr. Hovda is a professor of neurosurgery and of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA. He received his doctoral degree under the supervision of Dr. Dennis M. Feeney in the field of Physiological Psychology at the University of New Mexico. He completed his postdoctoral training in neurophysiology under Dr. Jamie Villablanca at UCLA.