1st Edition

Trends in Quorum Sensing and Quorum Quenching New Perspectives and Applications

Edited By Ravishankar Rai V, Jamuna A Bai Copyright 2020
    406 Pages 159 B/W Illustrations
    by CRC Press

    The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments.

    Key features:

    • Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching
    • Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance
    • Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings
    • Provides comprehensive coverage on molecular mechanisms in bacterial signaling

    1. Expanding Roles and Regulatory Networks of LadS/RetS in Pseudomonas aeruginosa

    [Chuanmin Zhou, Maryam Dadashi, and Min Wu]

    2. Autoinducer-1 Quorum Sensing Communication Mechanism in Gram-Negative Bacteria

    [Maria Cristina Dantas Vanetti, Deisy Guimarães Carneiro, Felipe Alves de Almeida,

    Erika Lorena Giraldo Vargas, Emília Maria França Lima, and Uelinton Manoel Pinto]

    3. Toward a Systematic Genomic Survey of Bacterial Quorum Sensing Genes: Cross Cutting Regulatory

    and Genomic Concepts

    [Juhász János, Sándor Pongor, and Balázs Ligeti]

    4. Old Acquaintances in a New Role: Regulation of Bacterial Communication Systems by Fatty Acids

    [Humberto Cortes-López, Martha Juárez-Rodríguez, Rodolfo García-Contreras, Marcos Soto-Hernández,

    and Israel Castillo-Juárez]

    5. Analysis of Quorum Sensing by Surface-Enhanced Raman Scattering Spectroscopy

    [Gustavo Bodelón, Sarah De Marchi-Lourenco, Jorge Pérez-Juste, Isabel Pastoriza-Santos, and Luis M. Liz-Marzán]

    6. Quorum Sensing in Pseudomonas aeruginosa: From Gene and Metabolic Networks to Bacterial Pathogenesis

    [Stephen K. Dolan, Cauã Antunes Westmann, Greicy Kelly Bonifacio Pereira, Stephen Trigg,

    Rafael Silva-Rocha, and Martin Welch]

    7. Quorum Sensing in Vibrios

    [H.A.D. Ruwandeepika, G.C.P. Fernando, J.L.P.C. Randika, and T.S.P. Jayaweera]

    8. Quorum Sensing in Lactic Acid Bacteria

    [Xiaoyang Pang, Jiaping Lv, Shuwen Zhang, Jing Lu, Obaroakpo Joy Ujiroghene, and Lan Yang]

    9. Role of N-acyl-homoserine Lactone QS Signals in Bacteria-Plant Interactions

    [Anton Hartmann and Michael Rothballer]

    10. Quorum Sensing and the Environment: Open Questions in Plant-Associated Bacteria

    [Ana Carolina del V. Leguina, Elisa V. Bertini, Mariano J. Lacosegliaz, Lucía I. Castellanos de Figueroa,

    and Carlos G. Nieto-Peñalver]

    11. In Silico Mining of Quorum Sensing Genes in Genomes and Metagenomes for Ecological

    and Evolutionary Studies

    [Iñigo de la Fuente and Jorge Barriuso]

    12. Bacterial Quorum Sensing in Multispecies Communities: The Presence, Functions and Applications

    [Chuan Hao Tan, Sujatha Subramoni, and Hyun-Suk Oh]

    13. Breaking Bad: Understanding How Bacterial Communication Regulates Biofilm-Related Oral Diseases

    [Andrea Muras and Ana Otero]

    14. Quorum Sensing in Autotrophic Nitrogen Removal Systems for Wastewater Treatment

    [Guangxue Wu, Zhaolu Feng, Yuepeng Sun, and Tianle Li]

    15. Mechanism and Types of Quorum Sensing Inhibitors

    [Christiane Chbib]

    16. Role of Small Volatile Signaling Molecules in the Regulation of Bacterial Antibiotic Resistance

    and Quorum Sensing Systems

    [José E. Belizário, Marcos Sulca-Lopez, Marcelo Sircili, and Joel Faintuch]

    17. Recent Advances in Science of Quorum Sensing: An Overview of Natural Product Inhibitors

    [Ana Ćirić, Petrović Jovana, Ivanov Marija, Kostić Marina, and Soković Marina]

    18. Nanomaterials as Quorum Sensing Inhibitors

    [Jamuna A. Bai and V. Ravishankar Rai]

    19. Phytochemical Compounds Targeting the Quorum Sensing System as a Tool to Reduce

    the Virulence Factors of Food Pathogenic Bacteria

    [Jesus M. Luna-Solorza, Francisco J. Vazquez-Armenta, A. Thalia Bernal-Mercado, M. Melissa Gutierrez-Pacheco,

    Filomena Nazzaro, and J. Fernando Ayala-Zavala]

    20. Targeting Bacterial Communication to Improve Bacterial Infections Therapy:

    Implications for Phage-Based Treatments—A Mathematical Perspective

    [Adrián Cazares, Rodolfo García-Contreras, Christina Kuttler, and Judith Pérez-Velázquez]

    21. Quorum Quenching Monoclonal Antibodies for the Detection and Treatment of Gram-Negative

    Bacterial Infections

    [Soumya Palliyil]

    22. Novel Intervention Techniques in the Food Industry

    [Carolina Ripolles-Avila and José Juan Rodríguez-Jerez]

    23. Quorum Sensing and Quorum Quenching in Food-Related Bacteria

    [Barbara Tomadoni and Alejandra Ponce]

    24. Quorum Quenching as an Anti-biofouling Strategy for Wastewater Reuse and Biofouling Affected Industries

    [Ioannis D. Kampouris, Dimitra C. Banti, and Petros Samaras]

    25. Application of Quorum Sensing Inhibitors in Anti-biofouling Membranes

    [Sunny C. Jiang and Leda K. Tse]

    26. Quorum Sensing and Quorum Quenching Based Antifouling Mechanism: A Paradigm Shift for Biofouling

    Mitigation in a Membrane Bioreactor (MBR)

    [Shabila Parveen, Sher Jamal Khan, and Imran Hashmi]

    27. Application of Quorum Quenching in the Control of Animal Bacterial Pathogens

    [Tsegay Teame, Rui Xia, Yalin Yang, Chenchen Gao, Fengli Zhang, Chao Ran, Zhen Zhang, Hongling Zhang,

    and Zhigang Zhou]


    Prof. Ravishankar Rai V received his M. Sc (1980) and Ph. D (1989) from University of Mysore, India. Currently, he is workingat the Department of Studies in Microbiology, University of Mysore, Mysore. His current research and publications in the food microbiology, microbial quorum sensing, microbial influenced corrosion and nanotechnology has been well received by the international scientific committee. His series of edited books with reputed publishers such as CRC Press and Wiley publications: Biotechnology: Concepts and Applications (2009), Microbial Food Safety and Preservation Techniques (2014), Beneficial Microbes in Fermented and Functional Foods (2014), Advances in Food Biotechnology (2015), Food Safety and Protection (2016) and Nanotechnology Applications in the Food Industry (2018) are comprehensive in nature and have contributions from international experts in the field. Prof. Rai has received awards from UNESCO Biotechnology Action Council Programme (Visiting Fellow, 1996), UGC Indo- Israel Culture Exchange Programme (1998), DBT Overseas Fellowship (2008), Indo- Hungarian Educational Exchange Programme fellowship (2011) and INSA – bilateral exchange fellowship (2015), Incoming Fellowship (2017) from Cardiff University, UK and invitation from Mauritius Research Council, Mauritius (2018) to conduct collaborative research with renowned scientists from international Universities. He has been awarded Bilateral Exchange Fellowship by Indian National Academy of Sciences to visit Germany (2019), Cambridge-Hamied Visiting Lecture Scheme (2019).

    Jamuna A. Bai has completed her MSc and PhD in Microbiology from University of Mysore, India. She is working as a Researcher in UGC sponsored University with Potential Excellence Project, University of Mysore, India. She has previously worked as ICMR Senior Research Fellow and carried research work on food safety, role of quorum sensing and biofilms in food-related bacteria and developing quorum-sensing inhibitors. Her research interests also include antimicrobial application of functionalized nanomaterials and peptides against pathogenic bacteria.  

    "The text provides a broad yet thorough examination of quorum sensing and methods of defeating it, featuring many detailed and well-written discussions covering an exhaustive array of related topics. Early chapters examine the regulation of cellular responses controlled by quorum sensing, as well as the types of signaling molecules used by various bacteria. Next are chapters focused on the specifics of quorum sensing in detail, for different bacteria. These chapters both expand and reinforce concepts from earlier chapters. The remainder of the book addresses quorum sensing as an important component of the mechanisms of pathogenicity and biofilm formation in different contexts, from food science to environmental engineering; some chapters present strategies to block these processes by interfering with quorum sensing (e.g., through monoclonal antibodies treatment). The book can serve as an effective introduction for those beginning to explore this field and a useful reference for experts."

    M. S. Kainz, Ripon College, Choice, Sep 2021