1st Edition

Tuberculosis The Microbe Host Interface

    M. tuberculosis remains one of the most successful human pathogens known. The causative agent of tuberculosis, it also has a unique ability to persist for years in the infected, apparently healthy host. This dormant organism can be reactivated years, even decades later to cause tuberculosis. This book reviews the most important state-of-the-art approaches currently used to study microbe-host interactions and highlights emerging methodologies.

    1. Mycobacterial Entry and Growth Using In Vitro Macrophage Models. 2. Analysis of Post-Phagocytic Events. 3. Analysis of Macrophage Signaling Following M. tuberculosis Infection. 4. The Acquired Immune Response to M. tuberculosis. 5. New In Vitro Models of Mycobacterial Pathogenesis. 6. Animal Models in the Analysis of Pathogenesis. 7. Analysis of Mycobacterium Tuberculosis Gene Expression in the Human Host. 8. Analysis of Latency. 9. Molecular Epidemiology: Clinical Utility, Public Health Implication, and Relevance to Pathogenesis.

    Biography

    Larry S. Schlesinger (The Ohio State University, USA) (Author), Lucy DesJardin (University of Iowa, USA) (Author)