Chapter 1 ◾ Comparative Genomics of Viruses
Thomas Rattei
Chapter 2 ◾ Current Techniques and Approaches for Metagenomic Exploration of Phage Diversity
Simon Roux and Mark Borodovsky
Chapter 3 ◾ Direct RNA Sequencing for Complete Viral Genomes
Sebastian Krautwurst, Ronald Dijkman, Volker Thiel,
Andi Krumbholz, and Manja Marz
Chapter 4 ◾ Computational Methods for Viral Quasispecies Assembly
Kim Philipp Jablonski and Niko Beerenwinkel
Chapter 5 ◾ Functional RNA Structures in the 3′ UTR of Mosquito-Borne Flaviviruses
Michael T. Wolfinger, Roman Ochsenreiter, and
Ivo L. Hofacker
vi ◾ Contents
Chapter 6 ◾ Structural Bioinformatics of Influenza Virus RNA Genomes
Alexander P. Gultyaev, René C.L. Olsthoorn,
Monique I. Spronken, and Mathilde Richard
Chapter 7
◾ Structural Genomics and Interactomics of SARS-COV2: Decoding Basic Building Blocks of the Coronavirus
Ziyang Gao, Senbao Lu, Oleksandr Narykov, Suhas
Srinivasan, and Dmitry Korkin
Chapter 8 ◾ Computational Tools for Discovery of CD8 T cell Epitopes and CTL Immune Escape in Viruses Causing Persistent Infections
Hadi Karimzadeh, Daniel Habermann, Daniel Hoffmann,
and Michael Roggendorf
Chapter 9 ◾ Virus-Host Transcriptomics
Caroline C. Friedel
Chapter 10 ◾ Sequence Classification with Machine Learning at the Example of Viral Host Prediction
Florian Mock and Manja Marz
Chapter 11 ◾ Master Regulators of Host Response to SARS-CoV-2 as Promising Targets for Drug Repurposing
Manasa KP , Kamilya Altynbekova, and Alexander Kel
Chapter 12 ◾ The Potential of Computational Genomics in the Design of Oncolytic Viruses
Henni Zommer and Tamir Tuller
Chapter 13 ◾ Sharing Knowledge in Virology
Edouard De Castro, Chantal Hulo, Patrick Masson, and
Philippe Le Mercier
Biography
Dmitrij Frishman is Professor for Bioinformatics at Munich Technical University (TUM)
Manja Marz is Professor for High-Throughput Sequencing Analysis at Friedrich Schiller University Jena
“Virology is progressing under the comfortable simplifications or reductionism and the disturbing recognition of complexity. Viruses are ubiquitous and diverse, and individual viral populations are exceedingly complex and dynamic, both genetically and phenotypically. As intracellular infection events are scrutinized at the single cell level of analysis, we are learning that virus-cell-organism interactions are multifaceted and intricate. Bioinformatics emerges to rescue virology amid a turmoil of new information in need of order. This book, edited by Manja Marz and Dimitrij Frishman, with outstanding contributing authors, will play the role of a lighthouse in a stormy ocean, to guide virologists on possible paths to follow.”
-- Esteban Domingo, Professor of Research at the Spanish National Research Council (CSIC), Madrid, Winter 2021
