1st Edition

Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis Pathogenesis, Treatment and Disease Control

Edited By Veer Singh, Ashish Kumar Copyright 2025
240 Pages 59 Color Illustrations
by CRC Press

240 Pages 59 Color Illustrations
by CRC Press

This reference book explores various aspects of visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL), including their pathophysiology, treatment options, and disease control strategies. The initial chapter provides an overview of VL, its global impact, and pathogenesis. It also examines the development of PKDL from VL, outlining the transition from the acute form of the... Read more

Preface

Acknowledgements

Editors

Contributors

Chapter 1 General Introduction to Visceral Leishmaniasis

Pinki Kumari, Sonali Vedika, and Ashish Kumar

Chapter 2 Geographical Distribution of VL and PKDL in India

Ravi Ranjan, Shobha Kumari, and Ashish Kumar

Chapter 3 Visceral Leishmaniasis as a Public Health Problem in India: Action Toward its Elimination

Sakshi Singh, Veer Singh, and Kumar Abhishek

Chapter 4 Pathogenesis of Visceral Leishmaniasis

Vikash Kumar, Divya Prasad, Ghufran Ahmed, and Ashish Kumar

Chapter 5 A Current Scenario of Drug Discovery Against Visceral Leishmaniasis

Kamal Singh, Bhavani R., and Swati Sharma

Chapter 6 Major Challenges in Visceral Leishmaniasis Treatment

Rishikesh Kumar and Krishna Pandey

Chapter 7 Post-kala-azar Dermal Leishmaniasis Development from Visceral Leishmaniasis

Ghufran Ahmed, Veer Singh, Dayakar Alti, Sonali Vedika, and Ashish Kumar

Chapter 8 Symptoms and Diagnosis of Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis

Priyanka Yadav, Kusum Yadav, Gyanendra Tripathi, and Pratibha Tiwari

Chapter 9 Molecular Mechanism of PKDL Development

Shobha Kumari, Pradeep Das, and Ashish Kumar

Chapter 10 Immunopathogenesis of Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis

Dayakar Alti, Vikash Kumar, and Ashish Kumar

Chapter 11 A Recent Update on Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis: Epidemiology, Diagnosis, and Treatments

Saurav Kumar Mishra and John J. Georrge

Chapter 12 Review of Existing Control Measures for VL and PKDL: Innovative Approaches to Vector Control, Case Management, Vaccine Development, and Community Education

Prashant Saxena, Madhvi Saxena, Anukrti Mishra, and Balashankar K.

Chapter 13 Public Health Implications and Challenges of VL and PKDL

Ritesh Kumar Tiwari, Gaurav Kumar Pandit, and Meenakshi Singh

Chapter 14 Role of Environmental Factors on the Development of PKDL

Moti Lal, Neelam, and Himanshu Gaur

Chapter 15 Arsenic and Antimony Toxicity in Drinking Water and Their Roles in the Development of PKDL

Manisha Verma, Mahesh S. Chivate, Vishal Singh, and Vishal Mishra

Chapter 16 Government Policies toward Providing Safe Drinking Water to the Public

Priyanka Yadav, Kusum Yadav, Mayank Saxena, and Isha Singh

Chapter 17 Factors Influencing the Development of Post-kala-azar Dermal Leishmaniasis

Himanshu N. Panchal, Divya J. Tandel, and Sapna Desai

Index

Biography

Dr. Veer Singh is currently working as Young Scientist (DHR) at the Department of Biochemistry, Rajendra Memorial Research Institute of Medical Sciences, Patna, India. He got PhD from the Indian Institute of Technology (Banaras Hindu University), Varanasi. He has more than 40 publications and his area of work involved Environmental contamination & toxicity, the role of drinking water heavy metals contamination in visceral leishmaniasis (VL) & post-kala-azar dermal leishmaniasis (PKDL) development.

Dr. Ashish Kumar is currently working as Scientist-C and Head of Department at the Department of Biochemistry, Rajendra Memorial Research Institute of Medical Sciences, and Patna, India. He has published more than 40 publications in International/national journals. He has received several awards and received several funding (sponsored projects) from many national and international agencies. Currently, 4 doctoral and 2 postdoctoral students are working under the supervision of Dr. Ashish Kumar. Dr. Kumar is working in the interdisciplinary area of life science. His work is mainly focused on visceral leishmaniasis (VL) and post kala-azar dermal leishmaniasis (PKDL). He is also working on VL and PKDL diagnosis, treatment and environmental impacts on disease development.