Women's Vascular Health  book cover
1st Edition

Women's Vascular Health

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ISBN 9780340809976
Published December 29, 2006 by CRC Press
506 Pages

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Book Description

This book brings together specialist authors from a variety of medical disciplines to give comprehensive coverage of the whole spectrum of women's vascular health. Covering coronary artery disease and its precursors, venous disease, thrombophilic defects, hormonal therapy and haemorrhagic problems, the content is divided into three sections.

Section one reviews generic issues including the pathophysiology of arteriosclerosis, metabolic factors in vascular disease, the epidemiology and management of CHD in women. The management of cardiac syndrome X and the problem of diabetes are also discussed here. The second section looks at women's vascular health as it applies to fertility issues and during pregnancy such as polycystic ovarian disease, menstrual dysfunction, the menopause, venous thromboembolism and haemorrhagic problems. In the concluding third section, hormonal therapy in women and in particular the oral contraceptive pill and hormone replacement therapies are covered.

The reader will be given a clear overview of the potential mechanisms whereby such therapy can act as a risk factor for arterial and venous disease, and will receive clear guidance regarding prescribing.

Table of Contents

      1. Epidemiology of vascular disease in women
      2. Pathophysiology of arterioscleriosis
      3. Metabolic risk factors for vascular disease in women
      4. Genetic factors in vascular disease
      5. Diabetes mellitus in women
      6. Haemostatic factors in vascular disease
      7. Congenital Thrombophilia and Venous Disease
      8. Acquired thrombophilia
      9. Congenital and acquired haemorrhagic problems
      10. The Vasculitides
      11. Anticoagulants / anticoagulants in pregnancy
      12. Antiplatelet agents
      13. Prophylaxis of venous and arterial thromboembolism in medical and surgical patients
      14. Management of coronary artery disease including syndrome X in women
      15. Peripheral vascular disease in women
      16. Cerebrovascular disease
      17. Cancer and thrombosis in women
      18. Management of DVT and PTE including longterm sequelae
      19. Irregular menstrual bleeding
      20. Polycystic ovarian syndrome and vascular disease
      21. The effect of pregnancy on the haemostatic and metabolic systems
      22. Venous thrombosis in pregnancy
      23. Venous thrombosis and ovarian stimulation
      24. Thrombophilia and pregnancy complications
      25. Heart disease in pregnancy
      26. Hypertension, pre-eclampsia and intrauterine growth restriction
      27. Thrombocytopenia in Pregnancy
      28. Gestational diabetes
      29. Maternal & fetal programming
      30. Epidemiology of the combined oral contraceptive pill and thrombosis
      31. The oral contraceptive pill, mechanisms of vascular risk and practical prescribing strategies for women with thrombotic problems
      32. Epidemiology of HRT and vascular disease
      33. Hormone replacement therapy and mechanism of vascular risk
      34. Practical strategies for HRT prescribing

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Ian A. Greer, Regius Professor of Obstetrics & Gynaecology, University of Glasgow, UK

Jeffrey Ginsberg, Professor of Medicine, McMaster University, Hamilton, Ontario, Canada

Charles D. Forbes, Professor of Medicine, Ninewells Hospital and Medical School, University of Dundee, UK


Written and edited by a unique combination of experts in obstetrics and gynecology, hemtaology, and medicine,  Women's Vascular Health presents a view of vascular disease in women that is much more holistic than is often acknowledged ... The timeliness of the book deserves emphasis ... the book does a remarkable job of assembling and incorporating even very recent pivotal clinical trial data that focus on women ... It correctly identifies the unique characteristics of women and their vascular health, making for a book that will help obstetricians, cardiologists, and primary care physicians alike offer a higher level of care to their female patients.

Ruchira Glaser, The New England Journal of Medicine