1st Edition

alpha2Adrenergic Receptors

By Lewis L. Lanier Copyright 1997
    226 Pages
    by CRC Press

    Preface, Contributors, Acknowledgements, Meeting Summary, Identification, Characterization and Subclassification of a.2-Adrenoceptors: An Overview, 1 0C2a Adrenergic Receptor Peptides and G Proteins: Structure and Mechanism, 2 Delineating Ligand-specific Structural Changes in Adrenergic Receptors by Use of Fluorescence Spectroscopy, 3 Characterization of Stereoselective Interactions of Catecholamines with the a2a-Adrenoceptor via Site Directed Mutagenesis, 4 Regulating Signal Transfer from Receptor to G-protein, 5 Caveolin, an Integral Membrane Protein Component of Caveolae Membranes In Vivo: Implications for Signal Transduction, 6 Molecular Determinants of Agonist-Independent Activity in Adrenergic Receptors, 7 a2-Adrenergic Receptor Activation and Intracellular Ca2+, 8 The Interface Between 0C2-Adrenoceptors and Tyrosine Kinase Signalling Pathways, 9 Differential Regulation of 0C2-Adrenergic Receptor Subtypes by Norepinephrine and Buffers, 10 Molecular Basis of 0C2-Adrenergic Receptor Subtype Regulation by Agonist, 11 a2-Adrenergic Receptor Subtypes Display Different Trafficking Itineraries in Madin-Darby Canine Kidney II Cells, 12 Intracellular 0C2a-Adrenergic Receptors in Neurons and GT1 Neurosecretory Cells, 13 Immunolocalization of Native ax-Adrenergic Receptor Subtypes: Differential Tissue and Subcellular Localization, 14 a2-Adrenergic Receptors in the Pathophysiology and Treatment of Depression, 15 Clinical Applications of ax-Adrenergic Agonists in the Perioperative Period - Neurobiologic Considerations, 16 0C2 and ai-Adrenergic Receptors in the Regulation of Peripheral Vascular Function, 17 Therapeutic Use of Ox-Adrenoceptor Agonists in Glaucoma, NDEX, ASPET COLLOQUIA

    Biography

    Lanier, Lewis L.