Danko D. Georgiev Author of Evaluating Organization Development
FEATURED AUTHOR

Danko D. Georgiev

Principal Investigator
Institute for Advanced Study

Danko D. Georgiev earned his M.D. from Medical University of Varna, Bulgaria, in 2004, and his Ph.D. in Pharmaceutical Sciences from Kanazawa University, Japan, in 2008 for his research in the area of neuronal differentiation. Dr. Georgiev currently conducts theoretical and applied interdisciplinary research across a number of disciplines including quantum physics, quantum chemistry, neuroscience, cognitive science, information science and mathematics.

Biography

Danko D. Georgiev earned his M.D. from Medical University of Varna, Bulgaria, in 2004, and his Ph.D. in Pharmaceutical Sciences from Kanazawa University, Japan, in 2008 for his research in the area of neuronal differentiation. He was a postdoctoral researcher in the Department of Psychiatry and Neurobiology at Kanazawa University, where he studied the molecular alterations in the cerebral cortex of subjects with schizophrenia. He held a two-year JSPS Postdoctoral Fellowship awarded by the Japan Society for the Promotion of Science, and was a short-term visiting scholar at the Department of Psychiatry, University of Pittsburgh. He was then a postdoctoral associate in the Department of Environmental and Occupational Health, University of Pittsburgh, where he studied the pathogenesis and pharmacological treatment of Alzheimer's disease. Dr. Georgiev is currently a principal investigator at the Institute for Advanced Study, Varna, Bulgaria. He has published over 40 research articles, some in world-renowned journals such as Physical Review A, Physica A, American Journal of Psychiatry, Schizophrenia Bulletin, and Journal of Neuroscience.

Education

    MD, Medical University of Varna, Bulgaria, 2004
    PhD, Kanazawa University, Japan, 2008

Areas of Research / Professional Expertise

    Neuroscience, Quantum Physics, Quantum Information, Philosophy of Mind, Consciousness

Websites

Books

Featured Title
 Featured Title - Quantum Information and Consciousness - 1st Edition book cover

Articles

Physical Review A 2022; 106 (6): 062437

Entanglement measures for two-particle quantum histories


Published: Dec 26, 2022 by Physical Review A 2022; 106 (6): 062437
Authors: Danko Georgiev, Eliahu Cohen
Subjects: Mathematics, Physics

We apply Feynman's sum-over-histories formalism to interacting bipartite quantum systems and introduce entanglement measures for bipartite quantum histories. Based on the Schmidt decomposition of the matrix comprised of the Feynman propagator complex coefficients, we prove that bipartite quantum histories are entangled if and only if the Schmidt rank of this matrix is larger than 1.

Modern Physics Letters B 2022; 36 (22): 2250101

Sensitivity of entanglement measures in bipartite pure quantum states


Published: Aug 29, 2022 by Modern Physics Letters B 2022; 36 (22): 2250101
Authors: Danko D. Georgiev, Stanley P. Gudder
Subjects: Mathematics, Physics

We have investigated the partial order between four entanglement measures: concurrence, tangle, entanglement robustness and Schmidt number. We have shown that among those measures, the concurrence and the Schmidt number have the highest and the lowest sensitivity to quantum entanglement, respectively. We have also employed state-dependent entanglement statistics to compute measurable correlations between the outcomes of quantum observables in agreement with the uncertainty principle.

Physics Letters A 2022; 448: 128319

Quantum tunneling of three-spine solitons through excentric barriers


Published: Jul 29, 2022 by Physics Letters A 2022; 448: 128319
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Life Science, Mathematics, Medicine, Physics

Macromolecular protein complexes catalyze essential physiological processes that sustain life. Interactions between protein subunits could increase the effective mass of certain peptide groups, thereby compartmentalizing protein α-helices. Excentric barriers, localized onto a single spine in the protein α-helix, are able to reflect or trap three-spine solitons as effectively as concentric barriers with comparable total mass.

Chaos, Solitons and Fractals 2022; 155: 111644

Thermal stability of solitons in protein α-helices


Published: Jan 29, 2022 by Chaos, Solitons and Fractals 2022; 155: 111644
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Life Science, Mathematics, Medicine, Physics

Protein α-helices provide an ordered biological environment that is conducive to soliton-assisted energy transport. The simulated stochastic quantum dynamics at physiological temperature, T=310 K, revealed that the cooperative action of three amide I exciton quanta ensures soliton lifetime of over 30 ps, during which the amide I energy could be transported along the entire extent of an 18-nm-long protein α-helix.

Biosystems 2021; 208: 104474

Quantum propensities in the brain cortex and free will


Published: Jul 14, 2021 by Biosystems 2021; 208: 104474
Authors: Danko D. Georgiev
Subjects: Biomedical Science, Chemistry, Life Science, Physics

We utilize quantum indeterminism to derive a quantitative measure for the amount of free will manifested by the brain cortical network during quantum measurement performed by the surrounding environment upon the neural constituents. Inherent biases in the quantum propensities for alternative physical outcomes provide varying amounts of free will, which can be quantified with the expected information gain from learning the actual course of action chosen by the nervous system.

Physical Review A 2021; 103(6): 062211

One-particle and two-particle visibilities in bipartite entangled Gaussian states


Published: Jun 08, 2021 by Physical Review A 2021; 103(6): 062211
Authors: Danko Georgiev, Leon Bello, Avishy Carmi, Eliahu Cohen
Subjects: Physics

We develop a method for quantifying the two-particle visibility in bipartite entangled Gaussian states using quantum measurement of a pair of two-particle observables that are compatible with the measured pair of single-particle observables. The method treats the two pairs of one-particle or two-particle observables on equal footing by formally identifying all four observable distributions as rotated marginal distributions of the original two-particle probability distribution.

Symmetry 2021; 13(5): 773

Quantum information in neural systems


Published: Apr 29, 2021 by Symmetry 2021; 13(5): 773
Authors: Danko D. Georgiev
Subjects: Biomedical Science, Chemistry, Life Science, Physics

We utilize the Schrödinger equation, together with the Planck–Einstein relation between energy and frequency, in order to determine the appropriate quantum dynamical timescale of conscious processes. Furthermore, with the help of a simple two-qubit toy model we illustrate the importance of non-zero interaction Hamiltonian for the generation of quantum entanglement and manifestation of observable correlations between different measurement outcomes.

Progress in Biophysics and Molecular Biology 2020; 158: 16-32

Quantum information theoretic approach to the mind–brain problem


Published: Dec 11, 2020 by Progress in Biophysics and Molecular Biology 2020; 158: 16-32
Authors: Danko D. Georgiev
Subjects: Biomedical Science, Life Science, Mathematics, Physics

Consciousness is comprised of unobservable quantum information integrated in quantum brain states, which explains the origin of the inner privacy of conscious experiences and revisits the dynamic timescale of conscious processes to picosecond conformational transitions of neural biomolecules. The observable brain is then an objective construction created from classical bits of information, which are bounded by Holevo's theorem.

Advances in Quantum Chemistry 2020; 82: 253-300

Quantum transport and utilization of free energy in protein α-helices


Published: Nov 18, 2020 by Advances in Quantum Chemistry 2020; 82: 253-300
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Life Science, Mathematics, Medicine, Physics

The essential biological processes that sustain life are catalyzed by protein nano-engines, which maintain living systems in far-from-equilibrium ordered states. To investigate energetic processes in proteins, we have analyzed the system of generalized Davydov equations that govern the quantum dynamics of multiple amide I exciton quanta propagating along the hydrogen-bonded peptide groups in α-helices.

Brain Research 2020; 1748: 147069

Computational capacity of pyramidal neurons in the cerebral cortex


Published: Aug 25, 2020 by Brain Research 2020; 1748: 147069
Authors: Danko D. Georgiev, Stefan K. Kolev, Eliahu Cohen, James F. Glazebrook
Subjects: Biomedical Science, Life Science, Mathematics, Medicine, Physics

Physical estimates of the total number and type of ions involved in neuronal electric spiking based on the obtained morphometric data, combined with energetics of neurotransmitter release and signaling fueled by glucose consumed by the active brain, support highly efficient cerebral computation performed at the thermodynamically allowed Landauer limit for implementation of irreversible logical operations.