1st Edition
Applied Pharmaceutical Practice and Nutraceuticals Natural Product Development
The pharmaceutical industry recognizes the shift to the use of natural products while also considering the serious concerns that have arisen regarding the claimed efficacy, quality, and safety of these products. This volume showcases how pharmaceutical and nutraceutical compounds from natural products can be used to cure or prevent diseases. The chapters explore the connections between agrochemicals and pharmaceuticals and the use of plants and plant products in the formulation and development of new pharmaceuticals and nutraceuticals.
1. Chalcone (1, 3-Diphenyl-2-Propene-1-One) Scaffold Bearing Natural Compounds as Nitric Oxide Inhibitors: Promising Anti-Edema Agents
Debarshi Kar Mahapatra, Sanjay Kumar Bharti, and Vivek Asati
2. Emblicanin-A and Emblicanin-B: Pharmacological and Nano-Pharmacotherapeutic Perspective for Healthcare Applications
Mohamad Taleuzzaman, Debarshi Kar Mahapatra, and Dipak Kumar Gupta
3. Recent In-Depth Insights of Nature-Based Anti-Worm Therapeutic Medications: Emerging Herbal Anthelmintics
Ankita Soni, Paras Kothari, and Debarshi Kar Mahapatra
4. Insights into the Recent Scientific Evidences of Natural Therapeutic Treasures as Diuretic Agents
Vaibhav Shende, Sameer Hedaoo, and Debarshi Kar Mahapatra
5. Reviewing the Available Herbal Resources for Treating Psoriasis: Safe and Alternative Way for Therapeutics
Shruti Dongare, Vaibhav Shende, and Debarshi Kar Mahapatra
6. Nutraceuticals and Brain Disorders
Akshada Atul Bakliwal et al.
7. 1, 3-Diphenyl-2-Propene-1-One Based Natural Product Anti-Diabetic Molecules as Inhibitors of Protein Tyrosine Phosphatase-1b (Ptp-1b)
Debarshi Kar Mahapatra, Sanjay Kumar Bharti, and Vivek Asati
8. Re-Highlighting the Potential Natural Resources for Treating or Managing the Ailments of Gastrointestinal Tract Origin
Vaibhav Shende et al.
9. Recent Advancements of Curcumin Analogs and Curcumin Formulations in Context to Modern Pharmacotherapeutics Perspectives
Animeshchandra G. M. Haldar, Kanhaiya M. Dadure, and Debarshi Kar Mahapatra
10. Emerging Highlights on Natural Prodrug Molecules with Multifarious Therapeutic Perspectives
Mojabir Hussen Ansari, Vaibhav Shende, and Debarshi Kar Mahapatra
11. Perspectives of Nature-Oriented Pharmacotherapeutics for the Effectual Management of Hemorrhoidal Symptoms
Taranpreet Kaur Bamrah, Mojabir Hussen Ansari, and Debarshi Kar Mahapatra
12. Effect of Light on Transport of Potassium Thiocyanate in Aqueous Solutions: Part I
Sónia I. G. Fangaia et al.
13. Drug Discovery, Drug Likeness Screening and Bioavailability: Development of Drug-Likeness Rule for Natural Products
E. D Ahire et al.
14. Biomolecular and Molecular Docking: A Modern Tool in Drug Discovery and Virtual Screening of Natural Products
Khemchand R. Surana et al.
Biography
Debarshi Kar Mahapatra, PhD, is Assistant Professor in the Department of Pharmaceutical Chemistry at Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India. He was formerly Assistant Professor in the Department of Pharmaceutical Chemistry, Kamla Nehru College of Pharmacy, RTM Nagpur University, Nagpur, India. He has published research, book chapters, reviews, and case studies in various reputed journals and has presented his work on several international platforms, for which he has received several important awards by a number of bodies. He has also authored the book titled Drug Design. Presently, he is serving as a reviewer and editorial board member for several journals of international repute.
Cristóbal Noé Aguilar, PhD, is Director of Research and Postgraduate Programs at the Universidad Autonoma de Coahuila, Mexico. Dr. Aguilar has published more than 160 papers in indexed journals, more than 40 articles in Mexican journals, and 250 contributions in scientific meetings. He has also published many book chapters, several Mexican books, four editions of international books, and more. He has been awarded several prestigious prizes and awards for his work. Dr. Aguilar is a member of the Mexican Academy of Science, the International Bioprocessing Association, Mexican Academy of Sciences, Mexican Society for Biotechology and Bioengineering, and the Mexican Association for Food Science and Biotechnology. He has developed more than 21 research projects, including six international exchange projects.
A. K. Haghi, PhD, is the author and editor of over 200 books, as well as over 1000 published papers in various journals and conference proceedings. Dr. Haghi has received several grants, consulted for a number of major corporations, and is a frequent speaker to national and international audiences. Since 1983, he served as professor at several universities. He is the former Editor-in-Chief of the International Journal of Chemoinformatics and Chemical Engineering and Polymers Research Journal and is on the editorial boards of many international journals. He is also a member of the Canadian Research and Development Center of Sciences and Cultures.
[REVIEWER'S EXPERT OPINION]
Patrick J. McDonnell, PharmD(Temple University School of Pharmacy)
**Description**
This book reviews the development of plant-based therapies directly or as a
starting point to develop and discover molecules for the treatment of disease.
This is the first edition, edited by three academics in the area of
pharmaceutical chemistry and employing the use of multi-authored chapters.
**Purpose**
The purpose is to present the perspectives of healthcare practitioners, such as
pharmacists and nutritionists, who have working knowledge of "nutraceuticals"
in the therapeutics of disease and how these molecules can be developed
therapeutically. These are worthy objectives; however, the chapters which are
multi-authored seem a bit "random" to me, without a generalized, edited
structure focusing on certain molecules, and then deviating to chapters on
specific disease states (like psoriasis) or organ systems.
**Audience**
From the objective it would appear the book would be written for practitioners
such as physicians, pharmacists, and nutritionists who may have a patient base
or practice that utilizes complementary medicine, namely nutraceuticals. But
after reviewing several of the chapters, it appears to be more of interest to
medicinal chemists and pharmaceutic professionals. The book has 26 contributing
authors. Sometimes when I see texts with multiple authors working on individual
chapters, the chapters do not flow consistently. This is the case in this book,
as there definitely is a bit of randomness to each chapter.
**Features**
The book covers some general topics like drug discovery and emerging targets for
potential natural therapeutics, but really deviates into what I perceive are
the authors' special areas of interest. For example, there is a chapter,
"Chalcone (1,3-diphenyl-2-propene-1-One) Scaffold Bearing Natural Compounds as
Nitric Oxide Inhibitors: Promising Antiedema Agents," that is rather specific
to what the author's objectives are (or what I would expect them to be). The
randomness of the chapters, though they may be detailed, is a bit of a shortcoming.
**Assessment**
As a pharmacy academician with an interest in natural products as a
practitioner, I found the book's randomness not as useful as I would have
liked. However, colleagues who are medicinal chemists and "drug discoverers"
may disagree, and I think they are more the target audience. As this is a first
edition, subsequent editions will be expected.
-----------------------------------------------------------
Weighted Numerical Score: 76 - 3 Stars
