Aptamers : Tools for Nanotherapy and Molecular Imaging book cover
1st Edition

Tools for Nanotherapy and Molecular Imaging

Edited By

Rakesh N. Veedu

ISBN 9789814669832
Published June 9, 2016 by Jenny Stanford Publishing
386 Pages 17 Color & 29 B/W Illustrations

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Book Description

Aptamers, often termed as ‘chemical antibodies,’ are an emerging class of synthetic ligands for efficient target-specific molecular recognition. The objective of this book is to highlight recent advances and potential of aptamers in various disease conditions. . This book focuses on the applications of aptamers in targeted nanotherapy, detection, and in molecular imaging in various disease conditions such as cancer, neurological diseases and infectious diseases.

Table of Contents

Aptamers-General Introduction. History of aptamer development. Peptide aptamers: Development and applications. Aptamer selection methodologies. Selection and application of catalytically active oligonucleotides. Aptamer Development for Therapeutic Applications. Stem-cell specific aptamers for targeted cancer therapy. Aptamers as therapeutic tools in neurological diseases. Aptamers in bacterial, viral and parasitic diseases. Aptamers for Targeted Drug Delivery & Nanotherapy. Aptamers as tools for targeted drug delivery. Aptamer-liposome conjugates: Current art and future prospects. Application of Aptamers as Biosensors. Aptamers in medical diagnosis. Aptamers for Target Specific Imaging. Molecular imaging utilizing aptamer-targeted probes. Clinical Utility Scope and Limitations of Aptamers. First therapeutic aptamer: VEGF-targeting Macugen. Aptamers: Scope, limitations and future prospects.

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