478 Pages
by
CRC Press
478 Pages
by
CRC Press
Also available as eBook on:
Carcinogens, like chemicals with other toxic hazards, often produce adverse effects only in specific organs or tissues. The factors determining whether a chemical induces cancer in an organ range from simple toxicokinetics to complex phenomena such as expression or lack of expression of specific genes.; This volume examines the site-specific factors involved in carcinogenesis in the liver,... Read more
Preface 1. General Principles of Chemical Carcinogenesis 2. Chemicals Causally Associated with Cancers in Humans and in Laboratory Animals: A Perfect Concordance 3. Hepatocarcinogenesis in the Rat 4. Susceptibility Factors of Gastrointestinal Tract Carcinogenesis 5. Renal Carcinogenesis 6. Urinary Bladder Carcinogenesis in the Rodent 7. Chemically Associated Respiratory Carcinogenesis in Rodents and in Humans 8. Upper Respiratory Tract Carcinogenesis in Experimental Animals and in Humans 9. Multistage Skin Carcinogenesis in Mice 10. Neurocarcinogenesis 11. Male Reproductive System 12. Carcinogenesis of the Hematopoietic System 13. Pathology Procedures in Laboratory Animal Carcinogenesis Studies
Biography
Michael P. Waalkes, Ph.D. Chief, Inorganic Carcinogenesis Section, Laboratory of Comparative Carcinogenesis. National Cancer Institute, Frederick Cancer Research and Development Center. Frederick, Maryland. Jerrold M. Ward, d.v.m., ph.d. Chief Veterinary and Tumor Pathology Section, Office of Laboratory Animal Science, National Cancer Institute Frederick Cancer Research and Development Center Frederick, Maryland.
