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Target Organ Toxicology Series


About the Series

The Target Organ Toxicology Series reviews the morphology, physiology, biochemistry, cellular biology, and developmental aspects of various target organs. Topics covered by books in the series include the incidence of chemically induced human disease related to the organ system, the reliability of laboratory data, methods used to estimate human risks, chemicals that adversely affect specific organs, and public health and environmental implications.

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Developmental Toxicology

Developmental Toxicology

3rd Edition

By Deborah K. Hansen, Barbara D. Abbott
November 14, 2018

Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and ...

Toxicology of the Gastrointestinal Tract, Second Edition

Toxicology of the Gastrointestinal Tract, Second Edition

2nd Edition

Edited By Shayne Cox Gad
October 30, 2018

The gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition ...

Neurotoxicology

Neurotoxicology

3rd Edition

By G. Jean Harry, Hugh A. Tilson
March 09, 2010

This new edition presents an integrated approach to neurotoxicology, the study of organisms’ responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects – from learning deficits, sensory disturbances in the ...

Toxicology of the Skin

Toxicology of the Skin

1st Edition

By Nancy A. Monteiro-Riviere
February 17, 2010

This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of ...

Endocrine Toxicology

Endocrine Toxicology

3rd Edition

Edited By J. Charles Eldridge, James T. Stevens
February 15, 2010

With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology’s ...

Adrenal Toxicology

Adrenal Toxicology

1st Edition

Edited By Philip W. Harvey, David J. Everett, Christopher J. Springall
October 22, 2008

Despite being regarded as the most common toxicological target in the endocrine system, the adrenal gland has often been neglected in regulatory testing. Adrenal Toxicology addresses the increased interest in adrenocortical toxicology and the need for a resource that makes techniques available to ...

Toxicant-Receptor Interactions Modulations of signal transduction and gene expression

Toxicant-Receptor Interactions: Modulations of signal transduction and gene expression

1st Edition

Edited By Michael Denison, William Helferich
August 10, 1998

Many of the toxic effects elicited by xenobiotics can be explained at the molecular level by their interaction with receptors or by disruption or interference with receptor-mediated signal transduction pathways. This volume describes molecular approaches and reviews of current research. It provides...

Toxicology of the Liver

Toxicology of the Liver

2nd Edition

Edited By Gabriel L Plaa, WR Hewitt
February 27, 1998

This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical...

Endocrine Toxicology

Endocrine Toxicology

2nd Edition

Edited By John A. Thomas
January 29, 1997

This text presents a range of topics from the molecular events surrounding hormone actions to epidemiologic studies of the effects of environmental and occupational chemicals on reproductive organs. The endocrine systems covered include the adrenal cortex, thyroid and parathyroid, gonads, and the ...

Carcinogenesis

Carcinogenesis

1st Edition

Edited By Michael P Waalkes
June 30, 1994

Carcinogens, like chemicals with other toxic hazards, often produce adverse effects only in specific organs or tissues. The factors determining whether a chemical induces cancer in an organ range from simple toxicokinetics to complex phenomena such as expression or lack of expression of specific ...

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