The Target Organ Toxicology Series reviews the morphology, physiology, biochemistry, cellular biology, and developmental aspects of various target organs. Topics covered by books in the series include the incidence of chemically induced human disease related to the organ system, the reliability of laboratory data, methods used to estimate human risks, chemicals that adversely affect specific organs, and public health and environmental implications.
Toxicology of the Skin
Toxicology of the Lung
By Deborah K. Hansen, Barbara D. Abbott
November 14, 2018
Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and ...
By Shayne C. Gad
October 30, 2018
The gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition ...
By G. Jean Harry, Hugh A. Tilson
March 09, 2010
This new edition presents an integrated approach to neurotoxicology, the study of organisms’ responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects – from learning deficits, sensory disturbances in the ...
By Nancy A. Monteiro-Riviere
February 17, 2010
This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of ...
By J. Charles Eldridge, James T. Stevens
February 15, 2010
With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology’s ...
By Philip W. Harvey, David J. Everett, Christopher J. Springall
October 22, 2008
Despite being regarded as the most common toxicological target in the endocrine system, the adrenal gland has often been neglected in regulatory testing. Adrenal Toxicology addresses the increased interest in adrenocortical toxicology and the need for a resource that makes techniques available to ...
By Donald E. Gardner
December 20, 2005
The most up-to-date treatment of inhalation toxicology available, Toxicology of the Lung, Fourth Edition examines the subject from a target-organ perspective. Completely revised and updated, the book includes contributions from an entirely new set of authors, each of them a leading international ...
By Michael Denison, William Helferich
August 10, 1998
Many of the toxic effects elicited by xenobiotics can be explained at the molecular level by their interaction with receptors or by disruption or interference with receptor-mediated signal transduction pathways. This volume describes molecular approaches and reviews of current research. It provides...
By Gabriel L Plaa, WR Hewitt
February 27, 1998
This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical...
By John A. Thomas, Howard D. Colby
January 29, 1997
This text presents a range of topics from the molecular events surrounding hormone actions to epidemiologic studies of the effects of environmental and occupational chemicals on reproductive organs. The endocrine systems covered include the adrenal cortex, thyroid and parathyroid, gonads, and the ...
By Michael P. Waalkes, Jerrold M. Ward
June 30, 1994
Carcinogens, like chemicals with other toxic hazards, often produce adverse effects only in specific organs or tissues. The factors determining whether a chemical induces cancer in an organ range from simple toxicokinetics to complex phenomena such as expression or lack of expression of specific ...