1st Edition

Chitin, Chitosan, Oligosaccharides and Their Derivatives
Biological Activities and Applications



ISBN 9781439816035
Published July 14, 2010 by CRC Press
672 Pages - 257 B/W Illustrations

USD $275.00

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Book Description

Biopolymers found in marine animals and plants offer tremendous, largely untapped pharmaceutical potential. Research shows that these biopolymers can be used to combat various infectious as well as inflammatory, oxidative, and carcinogenic factors. Chitin, Chitosan, Oligosaccharides and Their Derivatives: Biological Activities and Applications covers the key aspects of these therapeutically valuable biopolymers and their derivatives, namely, their properties, sources, production, and applications in food science and technology as well as biological, biomedical, industrial, and agricultural fields.

Contains more than 100 Tables & Figures and more than 800 References
Written by 40 international contributors who are leading experts in the field of natural biomaterials, this book provides an overview of the sources and production of chitin and chitosan derivatives. It also covers their:

  • Physical and chemical aspects
  • Structural modifications for biomedical applications
  • Biological activities, in particular, antimicrobial, anti-inflammatory, antioxidant, antihypertensive, anticancer, and antidiabetic activities
  • Biomedical applications, including their possible implications as drug, vaccine, and gene carriers
  • Industrial and agricultural applications

With their wide range of applications, the world is looking to biopolymers to serve as the basis for functional food- and drug development. This book is an important resource for those leading this effort.

Table of Contents

THE SOURCES AND PRODUCTION OF CHITIN AND CHITOSAN DERIVATIVES
Chitin and Chitosan from Terrestrial Organisms
Nitar Nwe, Tetsuya Furuike, and Hiroshi Tamura
Chitin and Chitosan from Marine Organisms
Wolfram M. Brück, John W. Slater, and Brian F. Carney
Chitin and Chitosan from Microorganisms
Zorica Knezevic-Jugovic, Zivomir Petronijevic, and Andrija Smelcerovic
Enzymatic Production of Chitin from Crustacean Shell Waste
Gyung-Hyun Jo, Ro-Dong Park, and Woo-Jin Jung
Continuous Production of Chitooligosaccharides by Enzymatic Hydrolysis
Se-Kwon Kim and Jae-Young Je
Biosynthesis of Cellulose–Chitosan Composite
Muenduen Phisalaphong, Nirun Jatupaiboon, and Jeerun Kingkaew
PHYSICAL AND CHEMICAL ASPECTS OF CHITIN AND CHITOSAN DERIVATIVES
Chemical Derivatization of Chitosan for Plasmid DNA Delivery: Present and Future
Wing-Fu Lai and Marie Chin-Mi Lin
X-Ray Diffraction Studies of Chitin, Chitosan, and Their Derivatives
Waldemar Maniukiewicz
Mechanical Properties of Chitosan and Chitosan–Poly(Vinyl Alcohol) Blend Films
Masaru Matsuo, Yumiko Nakano, Teruo Nakashima, and Yuezhen Bin
Electrostatic Properties of Chitosan
Won Jong Kim
Applications of Mass Spectrometry to Analyze Structure and Bioactivity of Chitooligosaccharides
Martin G. Peter and Marcos N. Eberlin
The Use of Various Types of NMR and IR Spectroscopy for Structural Characterization of Chitin and Chitosan
Mohammad Reza Kasaai
STRUCTURAL MODIFICATIONS OF CHITIN AND CHITOSAN DERIVATIVES
Chemical Modifications of Chitosan Intended for Biomedical Applications
Mani Prabaharan and Ashutosh Tiwari
Enzymatic Modifications of Chitin and Chitosan
Yong Zhao, Wan-Taek Ju, and Ro-Dong Park
BIOLOGICAL ACTIVITIES OF CHITIN AND CHITOSAN DERIVATIVES
Antimicrobial Activity of Chitin, Chitosan, and Their Oligosaccharides
Joydeep Dutta and Pradip Kumar Dutta
Anti-Inflammatory Activity of Chitin, Chitosan, and Their Derivatives
Moon-Moo Kim and Se-Kwon Kim
Chitosan Scaffolds for Bone Regeneration
Riccardo A.A. Muzzarelli
Antioxidative Activity of Chitin, Chitosan, and Their Derivatives
Pyo-Jam Park, Sushruta Koppula, and Se-Kwon Kim
Effects of Chitin, Chitosan, and Their Derivatives on Human Hemostasis
Se-Kwon Kim and Won-Kyo Jung
Antihypertensive Actions of Chitosan and Its Derivatives
Jae-Young Je and Chang-Bum Ahn
Anticancer Activity and Therapeutic Applications of Chitosan Nanoparticles
Hang T. Ta, Dave E. Dunstan, and Crispin R. Dass
Antidiabetic Activity and Cholesterol-Lowering Effect
Chang-Suk Kong and Se-Kwon Kim
BIOMEDICAL APPLICATIONS OF CHITIN AND CHITOSAN DERIVATIVES
Chitin/Chitosan Oligosaccharides: Effective Substrates for Functional Analysis of Chitinases/Chitosanases
Takayuki Ohnuma and Tamo Fukamizo
Low-Molecular-Weight Water-Soluble Chitosan with Free Amine Group for Drug Delivery
Mi-Kyeong Jang and Jae-Woon Nah
Chitosan/Chitosan Derivatives as Carriers and Immunoadjuvants in Vaccine Delivery
Suresh P. Vyas, Rishi Paliwal, and Shivani R. Paliwal
Chitosan-Conjugated DNA Nanoparticle Delivery Systems for Gene Therapy
R. Jayakumar, K. P. Chennazhi, S. V. Nair, Tetsuya Furuike, and Hiroshi Tamura
Chitinolytic Enzymes from the Moderately Thermophilic Bacterium Ralstonia sp. A-471: Characterization and Application
Mitsuhiro Ueda
Chitosan and Chitosan Derivatives as DNA and siRNA Carriers
Hu-Lin Jiang, Yun-Jaie Choi, Myung-Haing Cho, and Chong-Su Cho
Metabolic Pathway of Chitin and Its Oligosaccharides in Marine Bacterium Vibrios
Jae Kweon Park, Nemat O. Keyhani, and Saul Roseman
Medical Applications of Chitin and Chitosan: Going Forward
Eugene Khor
Radiation Functionalization and Applications of Chitosan and Its Derivatives
Maolin Zhai, Long Zhao, Ling Huang, Ling Xu, Liyong Yuan, and Min Wang
Applications of Chitosan Oligosaccharide and Glucosamine in Dentistry
Yoshihiko Hayashi
Applications of Chitosan and Its Derivatives in Veterinary Medicine
Sevda S¸enel
INDUSTRIAL APPLICATIONS OF CHITIN AND CHITOSAN DERIVATIVES
Separation Membranes from Chitin and Chitosan Derivatives
Tadashi Uragami
Hydrophobically Modified Acylated Chitosan Particles for Drug Delivery Applications: An Overview
R. Shelma and Chandra P. Sharma
Chitin, Chitosan, and Their Derivatives in Beverage Industry
Aurélie Bornet and Pierre-Louis Teissedre
Chitin Nanofibrils and Their Derivatives as Cosmeceuticals
P. Morganti
Chitin, Chitosan, and Their Oligosaccharides in Food Industry
Janak K. Vidanarachchi, Maheshika S. Kurukulasuriya, and Se-Kwon Kim
Chitin/Chitosan and Derivatives for Wastewater Treatment
P. N. Sudha
AGRICULTURAL AND BIOTECHNOLOGY APPLICATIONS OF CHITIN AND CHITOSAN AND THEIR DERIVATIVES
Chitin, Chitosan Derivatives Induced the Production of Secondary Metabolites and Plant Development through In Vitro and In Vivo Techniques
Abdul Bakrudeen Ali Ahmed and Se-Kwon Kim
Mechanism and Application of Chitin/Chitosan and Their Derivatives in Plant Protection
Heng Yin and Yuguang Du
Enhancing Crop Production with Chitosan and Its Derivatives
Nguyen Anh Dzung

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Editor(s)

Biography

Se-Kwon Kiro, Ph.D., Professor, Department of Chemistry Director, Marine Bioprocess Research Center, Pukyong National University, Busan, South Korea