1st Edition

Contact Urticaria Syndrome

Edited By Ana M. Gimenez-Arnau, Howard I. Maibach Copyright 2015
    310 Pages 28 B/W Illustrations
    by CRC Press

    Contact urticaria syndrome was first defined in 1975 and since then scientific interest has steadily increased. New cases are continuously being reported furnishing information on novel clinical features. A large number of compounds could be responsible for triggering the syndrome including fragrances, cosmetics, latex, preservatives, flavorings, and disinfectants.

    However, contact urticaria syndrome is often misdiagnosed in part due to a misinterpretation of its clinical manifestation and lack of knowledge of appropriate testing protocols and diagnostic programs. The latter have to be individualized for each patient based on the substance in question, medical history, possible concomitant disease, and clinical symptoms reported after exposure to the suspected culprit.

    Contact Urticaria Syndrome explains various aspects of this syndrome. The book discusses its definition, history, epidemiology, and occupational relevance. It also provides a detailed discussion of various triggers including proteins, chemical compounds, agricultural chemicals, metals, plants, foods, and other substances.

    The book describes known immunological and nonimmunological reactions along with diagnostic tools and test procedures. This comprehensive text is a helpful resource for dermatologists, toxicologists, immunologists, physicians, and other health care providers diagnosing and treating patients with contact urticaria syndrome. It summarizes clinical experience that makes it easier for providers to select the appropriate diagnostic tools and therapeutic approaches.

    Contact Urticaria Syndrome: Definition, History, Etiology, and Relevance; Ana M. Giménez-Arnau and Howard Maibach

    Contact Urticaria Syndrome: Epidemiology and Occupational Relevance; Kristiina Aalto-Korte and Sari Suomela

    Contact Urticaria Syndrome: How It Is Clinically Manifested and to Diagnose It; Ana M. Giménez-Arnau

    Mast Cell Biology and Its Role in the Immediate Skin Contact Reactions; Marcus Maurer, Frank Siebenhaar, Oliver Schmetzer, and Martin Metz

    The Oral Allergy Syndrome; Pascale Mathelier-Fusade

    Atopic Diathesis and Contact Urticaria Syndrome; M. Braire-Bourrel, F. Augey, F. Bérard, and J.F. Nicolas

    Proteins as Trigger Factors of Immediate Skin Contact Reactions; Pigatto Paolo Daniele and Rossano Hermes Valsecchi

    Chemical Compounds as Trigger Factors of Immediate Contact Skin Reactions; Elena Giménez-Arnau

    Nonimmunological Contact Urticaria; Vincent Cunanan and Arto Lahti

    Immunologic Contact Urticaria; Antti Lauerma

    Immunoglobulin E: Pathogenic Relevance in Urticaria and Eczema; Maria Estela Martinez-Escala, Eduardo Rozas-Muñoz, and Ana M. Giménez-Arnau

    Contact Urticaria Syndrome: Diagnostic Tools and Test Procedures; Charlotte G. Mortz and Klaus E. Andersen

    Molecular Diagnosis in Contact Urticaria Caused by Proteins; Joaquín Sastre

    Skin Tests and Specific IgE Determinations in the Diagnosis of Contact Urticaria and Respiratory Disease Caused by Low-Molecular-Weight Chemicals; Kristiina Aalto-Korte, Outi Kuuliala, and Eva Helaskoski

    Agricultural Chemicals; Vincent Cunanan, Christopher J. Dannaker, and Howard Maibach

    Animals and Animal Products as Causes of Contact Urticaria and Protein Contact Dermatitis; Päivikki Susitaival

    Contact Urticaria and Eczema from Dental Products; T. Rustemeyer

    Contact Urticaria Syndrome Induced by Drugs; Margarida Gonçalo

    Contact Urticaria, Dermatitis, and Respiratory Allergy Caused by Enzymes; Monica Stanciu and Denis Sasseville

    Contact Urticaria Syndrome from Epoxy Resin; Monica Hindsén and Magnus Bruze

    Contact Urticaria Syndrome from Foods and Food Derivatives; Pascale Mathelier-Fusade and Angèle Soria

    Cosmetic Components Causing Contact Urticaria Syndrome: An Update; Lien Verhulst and An Goossens

    Contact Urticaria Syndrome from Reactive Dyes in Textiles; Marléne Isaksson

    Hairdressing Products: Contact Urticaria Syndrome; Parastoo Davari and Howard H. Maibach

    Metals as a Cause of Contact Urticaria Syndrome; Majken G. Hougaard and Jacob P. Thyssen

    Skin Allergy Caused by Organic Acid Anhydrides; Riitta Jolanki and Kristiina Aalto-Korte

    Immediate Skin Contact Reactions from Plants; Evy Paulsen, Flemming Andersen, and Klaus E. Andersen

    Contact Urticaria to Preservatives and Disinfectants; Ryan Toholka and Rosemary Nixon

    Seminal Plasma Hypersensitivity and Immediate Contact Skin Reactions to Bodily Fluids; Jonathan A. Bernstein


    Ana M. Giménez-Arnau, MD, PhD, is a professor of dermatology at the Universitat Pompeu Fabra and Universitat Autònoma de Barcelona. She is also a consultant physician in dermatology and venereology in the Department of Dermatology at the Hospital del Mar, Barcelona. Dr. Giménez-Arnau was president of the 12th ESCD Congress in 2014. Her publications range from the 1995 article on chronic contact aquagenic urticaria to updated 2014 guidelines for the diagnosis and management of urticaria.

    Howard I. Maibach, MD, is a professor of dermatology at the University of California, San Francisco. Dr. Maibach’s publications range from the groundbreaking 1975 article on contact urticaria syndrome to the more recent books Dermatotoxicology (2012) and Handbook of Cosmetic Science and Technology (2014).