1st Edition

Data Driven Science for Clinically Actionable Knowledge in Diseases

254 Pages 59 B/W Illustrations
by Chapman & Hall

254 Pages 59 B/W Illustrations
by Chapman & Hall

254 Pages 59 B/W Illustrations
by Chapman & Hall

Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models,... Read more

Chapter 1. Understanding the Impact of Patient Journey Patterns on Health Outcomes for Patients with Diabetes

Jamil Daher, Patricia Correll, Paul J. Kennedy, and Barry Drake

Chapter 2. COVID-19 Impact Analysis on Patients with Complex Health Conditions: A Literature Review

Xueping Peng, Guodong Long, Peng Yan, Wensi Tang, and Allison Clarke

Chapter 3. Estimating the Relative Contribution of Transmission to the Prevalence of Drug Resistance in Tuberculosis

Tanzila K. Chowdhury, Laurence A.F. Park, Glenn Stone, Mark M Tanaka, and Andrew Francis

Chapter 4. A Novel Diagnosis System for Parkinson’s Disease Based on Ensemble Random Forest

Arkadip Ray and Avijit Kumar Chaudhuri

Chapter 5. Harmonization of Brain Data across Sites and Scanners

Ilias Aitterrami, Edouard Duchesnay, and Carol Anne Hargreaves

Chapter 6. Feature-Ranking Methods for RNA Sequencing Data

Girija Rani Karetla, Quang Vinh Nguyen, Simeon J. Simoff, Daniel R. Catchpoole, and Paul J. Kennedy

Chapter 7. Graph Neural Networks for Brain Tumour Segmentation

Nico Loesch and Marc Fischer

Chapter 8. Biomedical Data Analytics and Visualisation—A Methodological Framework

Quang Vinh Nguyen, Zhonglin Qu, Chng Wei Lau, Yezihalem Tegegne, Jesse Tran, Girija Rani Karetla, Paul J. Kennedy, Simeon J. Simoff, and Daniel R. Catchpoole

Chapter 9. Visualisation for Explainable Machine Learning in Biomedical Data Analysis

Zhonglin Qu, Simeon J. Simoff, Paul J. Kennedy, Daniel R. Catchpoole, and Quang Vinh Nguyen

Chapter 10. Visual Communication and Trust in the Health Domain

Quang Vinh Nguyen, Paul J. Kennedy, Simeon J. Simoff, and Daniel R. Catchpoole

Biography

Daniel R. Catchpoole is the Group Leader of the Tumour Bank, Children’s Cancer Research Unit, Children’s Hospital, Westmead, Australia. He is also affiliated with the Faculty of Medicine at the University of Sydney and the Department of Information Technology at the University of Technology Sydney.

Simeon J. Simoff is the Cluster Pro Vice Chancellor (Science, Technology, Engineering and Mathematics) and Dean of the School of Computer, Data and Mathematical Sciences at Western Sydney University.

Paul J. Kennedy is the Director of the Biomedical Data Science Laboratory at the Australia Artificial Intelligence Institute and the Head of Computer Science in the Faculty of Engineering and Information Technology at the University of Technology Sydney.

Quang Vinh Nguyen is the Director of Academic Programs for Postgraduate ICT at the School of Computer, Data and Mathematical Sciences and the MARCS Institute for Brain, Behaviour and Development at Western Sydney University.

"The intersection of the computational, biological, and medical sciences is poised to revolutionize personalized medicine across a vast spectrum of diseases and in low, medium, and high income countries. This new book, Data Driven Science for Clinically Actionable Knowledge in Diseases, serves as a fantastic overview of the space for all stakeholders. The text enables readers to learn both about the trajectory of the space, and to identify specific technical use cases where success has been shown and which can be re-deployed into new systems."

– Dr Noah Berlow, First Ascent Biomedical

"Health data is inherently complex and collected via wildly diverse channels. This book shows how leveraging health data is difficult, difficult to collect, and difficult to synthesise, but how much patient care can be improved when it is done well."

– Prof David Skillicorn, Queens University, Kingston, Ontario, Canada