1st Edition
Data Driven Science for Clinically Actionable Knowledge in Diseases
Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction.
This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments.
By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.
Chapter 1. Understanding the Impact of Patient Journey Patterns on Health Outcomes for Patients with Diabetes
Jamil Daher, Patricia Correll, Paul J. Kennedy, and Barry Drake
Chapter 2. COVID-19 Impact Analysis on Patients with Complex Health Conditions: A Literature Review
Xueping Peng, Guodong Long, Peng Yan, Wensi Tang, and Allison Clarke
Chapter 3. Estimating the Relative Contribution of Transmission to the Prevalence of Drug Resistance in Tuberculosis
Tanzila K. Chowdhury, Laurence A.F. Park, Glenn Stone, Mark M Tanaka, and Andrew Francis
Chapter 4. A Novel Diagnosis System for Parkinson’s Disease Based on Ensemble Random Forest
Arkadip Ray and Avijit Kumar Chaudhuri
Chapter 5. Harmonization of Brain Data across Sites and Scanners
Ilias Aitterrami, Edouard Duchesnay, and Carol Anne Hargreaves
Chapter 6. Feature-Ranking Methods for RNA Sequencing Data
Girija Rani Karetla, Quang Vinh Nguyen, Simeon J. Simoff, Daniel R. Catchpoole, and Paul J. Kennedy
Chapter 7. Graph Neural Networks for Brain Tumour Segmentation
Nico Loesch and Marc Fischer
Chapter 8. Biomedical Data Analytics and Visualisation—A Methodological Framework
Quang Vinh Nguyen, Zhonglin Qu, Chng Wei Lau, Yezihalem Tegegne, Jesse Tran, Girija Rani Karetla, Paul J. Kennedy, Simeon J. Simoff, and Daniel R. Catchpoole
Chapter 9. Visualisation for Explainable Machine Learning in Biomedical Data Analysis
Zhonglin Qu, Simeon J. Simoff, Paul J. Kennedy, Daniel R. Catchpoole, and Quang Vinh Nguyen
Chapter 10. Visual Communication and Trust in the Health Domain
Quang Vinh Nguyen, Paul J. Kennedy, Simeon J. Simoff, and Daniel R. Catchpoole
Biography
Daniel R. Catchpoole is the Group Leader of the Tumour Bank, Children’s Cancer Research Unit, Children’s Hospital, Westmead, Australia. He is also affiliated with the Faculty of Medicine at the University of Sydney and the Department of Information Technology at the University of Technology Sydney.
Simeon J. Simoff is the Cluster Pro Vice Chancellor (Science, Technology, Engineering and Mathematics) and Dean of the School of Computer, Data and Mathematical Sciences at Western Sydney University.
Paul J. Kennedy is the Director of the Biomedical Data Science Laboratory at the Australia Artificial Intelligence Institute and the Head of Computer Science in the Faculty of Engineering and Information Technology at the University of Technology Sydney.
Quang Vinh Nguyen is the Director of Academic Programs for Postgraduate ICT at the School of Computer, Data and Mathematical Sciences and the MARCS Institute for Brain, Behaviour and Development at Western Sydney University.
"The intersection of the computational, biological, and medical sciences is poised to revolutionize personalized medicine across a vast spectrum of diseases and in low, medium, and high income countries. This new book, Data Driven Science for Clinically Actionable Knowledge in Diseases, serves as a fantastic overview of the space for all stakeholders. The text enables readers to learn both about the trajectory of the space, and to identify specific technical use cases where success has been shown and which can be re-deployed into new systems."
– Dr Noah Berlow, First Ascent Biomedical
"Health data is inherently complex and collected via wildly diverse channels. This book shows how leveraging health data is difficult, difficult to collect, and difficult to synthesise, but how much patient care can be improved when it is done well."
– Prof David Skillicorn, Queens University, Kingston, Ontario, Canada
