1st Edition
Endothelin Receptors From the Gene to the Human
By Robert R. Ruffolo, Jr.
Copyright 1995
304 Pages
by
CRC Press
304 Pages
by
CRC Press
Also available as eBook on:
Since the discovery of endothelin, major advances have been made in understanding the molecular structure and function of the endothelin receptors. At least two subtypes of receptors, designated ETA and ETB, have been identified through biochemical and pharmacological techniques. These subtypes are cloned and expressed and additional subtypes appear to exist. The biochemical events involved in the... Read more
Introduction: Endothelin Receptors, E.H. Ohlstein and R.R. Ruffolo, Jr.
Endothelin Receptor Subclassification, E.H. Ohlstein, P. Nambi, and R.R. Ruffolo, Jr.
Molecular Biology of Endothelin Receptors, D.J. Bergsma, N. Elshourbagy, and C. Kumar
Signal Transduction Processes Involved in Endothelin-Mediated Responses, P. Nambi, C. Kumar, and E.H. Ohlstein
Endothelin Receptor Antagonists, J.D. Elliott, M.A. Lago, and C.E. Peishoff
Functions Mediated by Peripheral Endothelin Receptors, E.H. Ohlstein, S. Douglas, D.P. Brooks, D.W.P. Hay, G.Z. Feuerstein, and R.R. Ruffolo, Jr.
Endothelin in the Central Nervous System, R.N. Willette, G.Z. Feuerstein, and F.C. Barone
The Role of Endothelin in Human Disease: Implications and Potential Therapeutic Intervention, D.K. Jorkasky, D.W.P. Hay, and M.I. Freed
Index
Endothelin Receptor Subclassification, E.H. Ohlstein, P. Nambi, and R.R. Ruffolo, Jr.
Molecular Biology of Endothelin Receptors, D.J. Bergsma, N. Elshourbagy, and C. Kumar
Signal Transduction Processes Involved in Endothelin-Mediated Responses, P. Nambi, C. Kumar, and E.H. Ohlstein
Endothelin Receptor Antagonists, J.D. Elliott, M.A. Lago, and C.E. Peishoff
Functions Mediated by Peripheral Endothelin Receptors, E.H. Ohlstein, S. Douglas, D.P. Brooks, D.W.P. Hay, G.Z. Feuerstein, and R.R. Ruffolo, Jr.
Endothelin in the Central Nervous System, R.N. Willette, G.Z. Feuerstein, and F.C. Barone
The Role of Endothelin in Human Disease: Implications and Potential Therapeutic Intervention, D.K. Jorkasky, D.W.P. Hay, and M.I. Freed
Index
Biography
Robert R. Ruffolo Jr.
"This book is recommended as an addition to the libraries of institutions and individual researchers actively studying the physiological and/or pathophysicological role of endothelin."
- J. Med. Chem., 1996, 39(3)
