This comprehensive review discusses the biosynthesis and catabolism of flavonoids and their regulation in plants. This interesting work approaches the subject matter from both a historical and methodological point of view. It places emphasis on key regulatory enzymic steps in the two pathways leading to the flavonoid basic units as well as the overall pathway within the flavonoid group. This special volume focuses on the known cell-free enzymology at the C15 level, as well as isotopic tracer studies involving the still unknown enzymic steps. This up-to-date text is an excellent resource for all plant physiologists, biological chemists, phytochemists and chemical ecologists.
General Aspects of Chemistry and Metabolism of Flavonoids. Origin of Phenylpropanoid (C6-C3) and Acetate Units. Chalcone Synthase and Chalcone Isomerase: "Flavanone Synthase." Biosynthesis of Flavanones and 3-Hydroxyflavanones (Dihydroflavonols): The "Grid" Pattern of Basic Hydroxylations of the B- and C-Rings. Flavone and Flavonol Pathways. Pathway to Proanthocyanidins (Condensed Tannins), Flavan-3-ols, and Unsubstituted Flavans. Anthocyanidin-Anthocyanin Pathway. Isoflavonoid Pathways. Chalcones, Dihydrochalcones, and Aurones. Biflavonoids. Secondary Changes: Recycling and Degradation of Flavonoids. Competitive Pathways in Secondary Metabolism. Regulation. Impact of Methodology on Flavonoid Metabolism. Metabolic and Evolutionary Aspects of the Basic Function of Flavonoids. General History of Studies of Flavonoid Metabolism. Index.