Functional and Molecular Glycobiology  book cover
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Functional and Molecular Glycobiology



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ISBN 9781859960226
Published June 30, 2002 by Garland Science
298 Pages

 
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Book Description

Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans. It looks at the functional role of glycoconjugate compounds in normal cellular processes, in both disease and development. The book also describes how these compounds can be studied, analysed and manipulated for use in biotechnology. Functional and Molecular Glycobiology is a unique introduction to the field bridging the gap between introductory books and current research.

Table of Contents

Ch 1. An introduction to carbohydrate chemistry. Ch 2. Enzymes of glycosylation - the glycosyltransferases. Ch 3. Polysaccharides. Ch 4. N-linked glycoproteins. Ch 5. O-linked (mucin-type) glycoproteins. Ch 6. O-glcnac glycosylation of nuclear and cytosolic proteins. Ch 7. Species specific and unusual types of glycoprotein glycosylation. Ch 8. Glycoconjugates of the extracellular matrix of animals. Ch 9. Glycosphingolipids. Ch 10. Glycan chain extension and some common and important glycan structures. Ch 11. Sialic acids. Ch 12. Glycosylphosphatidylinositol (gpi)-anchored proteins. Ch 13. Carbohydrate-binding proteins (lectins). Ch 14. Tools for carbohydrate analysis. Ch 15. Modulation of glycan expression using inhibitors of N- and O-linked glycoconjugate processing, and transgenic technology. Ch 16. Disease processes in which carbohydrates are involved. Ch 17. Carbohydrate-based therapeutics. Ch18. Carbohydrate biotechnology.

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