1st Edition

Handbook of Full-Field Optical Coherence Microscopy Technology and Applications

Edited By Arnaud Dubois Copyright 2016
    790 Pages 81 Color & 239 B/W Illustrations
    by Jenny Stanford Publishing

    790 Pages 81 Color & 239 B/W Illustrations
    by Jenny Stanford Publishing

    Full-field optical coherence microscopy (FF-OCM) is an imaging technique that provides cross-sectional views of the subsurface microstructure of semitransparent objects. The technology is based on low-coherence interference microscopy, which uses an area camera for en face imaging of the full-field illuminated object. FF-OCM benefits from the lateral imaging resolution of optical microscopy along with the capacity of optical axial sectioning at micrometer-scale resolution. The technique can be employed in diverse applications, in particular for non-invasive examination of biological tissues.

    This handbook is the first to be entirely devoted to FF-OCM. It is organized into four parts with a total of 21 chapters written by recognized experts and major contributors to the field. After a general introduction to FF-OCM, the fundamental characteristics of the technology are analyzed and discussed theoretically. The main technological developments of FF-OCM for improving the image acquisition speed and for endoscopic imaging are presented in part II. Extensions of FF-OCM for image contrast enhancement or functional imaging are reported in part III. The last part of the book provides an overview of possible applications of FF-OCM in medicine, biology, and materials science.

    A comprehensive compilation of self-contained chapters written by leading experts, this handbook is a definitive guide to the theoretical analyses, technological developments, and applications of FF-OCM. Using the rich information the book is replete with, a wide range of readers, from scientists and physicists to engineers as well as clinicians and biomedical researchers, can get a handle on the latest major advances in FF-OCM.

    Introduction to full-field optical coherence microscopy

    Arnaud Dubois

    Theory of imaging and coherence effects in full-field optical coherence microscopy

    Anton Grebenyuk and Vladimir Ryabukho

    Spatio-temporal coherence effects in full-field optical coherence tomography

    Ibrahim Abdulhalim

    Cross-talk in full-field optical coherence tomography

    Boris Karamata, Marcel Leutenegger, and Theo Lasser

    Signal processing methods in full-field optical coherence microscopy

    Igor Gurov

    High-speed image acquisition techniques of full-field optical coherence tomography

    Woo June Choi, Kwan Seob Park, Gihyeon Min, and Byeong Ha Lee

    Toward single-shot imaging in full-field optical coherence tomography

    Bettina Heise

    Frequency-domain full-field optical coherence tomography

    Rainer Leitgeb, Abhishek Kumar, and Wolfgang Drexler

    Full-field OCM for endoscopy

    Anne Latrive and Claude Boccara

    Full-field optical coherence tomography and microscopy using spatially incoherent monochromatic light

    Dalip Singh Mehta, Vishal Srivastava, Sreyankar Nandy, Azeem Ahmad, and Vishesh Dubey

    Real time and high quality on-line 4D FF-OCT using continuous fringe scanning with a high speed camera and FPGA image processing

    P.C. Montgomery, F. Anstotz, D. Montaner, and F. Salzenstein

    Digital interference holography for tomographic imaging

    Lingfeng Yu, Mariana Potcoava, and Myung Kim

    Technological extensions of FF-OCM for multi-contrast imaging

    Arnaud Dubois

    Spectroscopic full-field optical coherence tomography

    Julien Moreau

    Multi-Wavelength Full-Field Optical Coherence Tomography

    Mariana Potcoava, Nilanthi Warnasooriya, Lingfeng Yu, and Myung K. Kim

    Dual-modality full-field optical coherence and fluorescence sectioning microscopy: toward all optical digital pathology on freshly excised tissue

    Fabrice Harms

    Full-field optical coherence tomography for rapid histological evaluation of ex vivo tissues

    Manu Jain and Sushmita Mukherjee

    FF-OCT imaging: a tool for human breast and brain tissue characterization

    Osnath Assayag

    Full-field optical coherence microscopy in ophthalmology

    Gael Latour, Kate Grieve, G. Georges, L. Siozade, Michel Paques, V. Borderie, L. Hoffart, and Carole Deumié

    Investigation of spindle structure and embryo development for pre-implantation genetic diagnosis by subcellular live imaging with FF-OCT

    Ping Xue and Jing-gao Zheng

    FF-OCT for nondestructive material characterization and evaluation

    David Stifter


    Arnaud Dubois is a professor at Institut d’Optique Graduate School in Palaiseau, France. He received his PhD from Paris-Saclay University in 1997. His current research interests concern biophotonics and optical imaging. A pioneer in full-field optical coherence microscopy in the early 2000s, Prof. Dubois has since been a major contributor to the development of this technology. In 2014 he co-founded DAMAE Medical, a company working on an innovative optical coherence microscopy technique for in situ diagnosis of skin diseases. He is the author or coauthor of more than 100 research articles and 12 book chapters. He has participated in about 200 conferences and has 5 patents to his credit. His teaching activities cover most aspects of optics at the master’s level.