Handbook of Imaging in Biological Mechanics: 1st Edition (Pack - Book and Online) book cover

Handbook of Imaging in Biological Mechanics

1st Edition

Edited by Corey P. Neu, Guy M. Genin

CRC Press

579 pages | 127 Color Illus. | 294 B/W Illus.

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pub: 2014-10-24
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Description

Emerging imaging techniques have opened new fronts to investigate tissues, cells, and proteins. Transformative technologies such as microCT scans, super-resolution microscopy, fluorescence-based tools, and other methods now allow us to study the mechanics of cancer, dissect the origins of cellular force regulation, and examine biological specimens at the nanoscale.

The Handbook of Imaging in Biological Mechanics presents the spectrum of imaging techniques used for noninvasive visualization of the morphology and mechanics of the large and small—from organs to individual macromolecules.

The handbook presents optimal imaging technologies to study deformation, stress, and constitutive behavior of tissues, cells, and proteins. It also describes a suite of technologies available for probing the mechanics of surfaces, membranes, and single molecules. With chapters authored by highly recognized experts in their area, the handbook covers the entire spectrum of biomechanical and mechanobiologic imaging technologies available today.

Table of Contents

INTRODUCTION

Imaging in Biological Mechanics; Corey P. Neu and Guy M. Genin

TISSUE AND ORGAN IMAGING METHODS: MAGNETIC RESONANCE IMAGING METHODS

MRI Tagging of the Heart; Leon Axel and Solae Chung

Frequency-Domain Analysis of Tagged MRI and Imaging Strategies; Khaled Z. Abd-Elmoniem, Vijay Parthasarathy, and Jerry L. Prince

Magnetic Resonance Elastography; Jiming Zhang and Raja Muthupillai

Magnetic Resonance Elastography of the Brain; Philip V. Bayly, Erik H. Clayton, Guy M. Genin, and Ruth J. Okamoto

Displacements under Applied Loading by MRI in Soft Biomaterials and Tissues; Corey P. Neu

TISSUE AND ORGAN IMAGING METHODS: ULTRASOUND

Ultrasound and Optical Methods for Dynamic Viscoelastic Imaging; Yue Wang, Steven G. Adie, Stephen A. Boppart, and Michael F. Insana

Ultrasound Imaging of Mechanical Properties of Cancers; Brian S. Garra

TISSUE AND ORGAN IMAGING METHODS: RADIOGRAPHY AND COMPUTED TOMOGRAPHY

Computed Tomography Image-Based Kinematic Analysis: An Overview; Douglas C. Moore, Eni Halilaj, Tarpit K. Patel, and Joseph J. Crisco III

Contrast-Enhanced MicroCT Imaging; David Reece, Angela Lin, and Robert E. Guldberg

TISSUE AND ORGAN IMAGING METHODS: HIGH THROUGHPUT AND IMAGE QUANTIFICATION

Application of Digital Image Correlation for Multiscale Biomechanics; Hui Wang, William Lai, Antonia Antoniou, and Ashraf Bastawros

Image-Based Estimation of Passive Myocardial Properties Using Finite Element Modeling; Alexander I. Veress, Benjamin R. Coleman, Genevieve Farrar, W. Paul Segars, and Brian C. Fabien

Particle Image Velocimetry for Biological Mechanics; Zachary J. Taylor, Roi Gurka, and Alex Liberzon

High-Throughput Imaging Methodologies for Biomechanical Testing; Yu Long Han, Guoyou Huang, Lin Wang, Xiaoxi Fan, Fei Li, Pengfei Wang, Tian Jian Lu, and Feng Xu

TISSUE AND ORGAN IMAGING METHODS: MULTISCALE IMAGING AND MODELING

Nonlinear and Poroelastic Biomechanical Imaging: Elastography Beyond Young’s Modulus; Paul E. Barbone, Assad A. Oberai, Jeffrey C. Bamber, Gearóid P. Berry, Jean-François Dord, Elizabete Rodrigues Ferreira, Sevan Goenezen, and Timothy J. Hall

Quantitative Anatomy Using Design-Based Stereology; Peter R. Mouton

Brain Shift Compensation via Intraoperative Imaging and Data Assimilation; Songbai Ji, Xiaoyao Fan, David W. Roberts, Alex Hartov, Timothy J. Schaewe, David A. Simon, and Keith D. Paulsen

Noninvasive Determination of Material Properties for Biological Materials; Kent Butz, Deva Chan, Corey P. Neu, and Eric A. Nauman

CELLULAR AND MOLECULAR IMAGING METHODS: MICROENVIRONMENTS: NATIVE ECM

Nonlinear Optical Microscopy in Biomechanics; Jessica C. Mansfield, James S. Bell, Julian Moger, and C. Peter Winlove

Collagen–Cell Interactions in Three-Dimensional Microenvironments; Sherry L. Voytik-Harbin and Bumsoo Han

Integrated Modeling and Imaging for Quantifying the Mechanics of Cells in Three-Dimensional Culture; Guy M. Genin and Elliot L. Elson

CELLULAR AND MOLECULAR IMAGING METHODS: MICROENVIRONMENTS: IN VITRO CULTURE SYSTEMS

Measurement of Cellular Forces via Traction Force Microscopy; Wesley R. Legant

Cell Interactions in Wire (Fiber)-Based Structures and Scaffolds; Kevin Sheets, Puja Sharma, Brian Koons, and Amrinder Nain

Mechanical Stretch Assays in Cell Culture Systems; Abhishek Tondon, Candice Haase, and Roland Kaunas

CELLULAR AND MOLECULAR IMAGING METHODS: CELLULAR AND SUBCELLULAR BIOPHYSICS

Micropipette Aspiration and Subcellular Biophysics; Baoyu Liu and Jin-Yu Shao

Scanning Probe Investigation of Cellular and Subcellular Biomechanics; Sirimuvva Tadepalli, Keng-Ku Liu, and Srikanth Singamaneni

Fluorescence-Based Tools for Quantifying Adhesion Dynamics; Haguy Wolfenson

Nanoscale Mechanical Testing of FIB-Isolated Biological Specimens; Ines Jimenez-Palomar, Russell J. Bailey, and Asa H. Barber

Imaging Cellular Mechanotransduction Using FRET-Based Biosensors;Qiaoqiao Wan, Yu-Hui Lai, and Sungsoo Na

Intracellular Particle Tracking Microrheology;Michelle R. Dawson, Yiider Tseng, Jerry S.H. Lee, and Kathleen M. McAndrews

CELLULAR AND MOLECULAR IMAGING METHODS: NUCLEAR BIOPHYSICS

Probing Chromatin Structure and Dynamics Using Fluorescence Anisotropy Imaging; Ekta Makhija, K. Venkatesan Iyer, Shefali Talwar, and G.V. Shivashankar

Nuclear Imaging in Mechanobiology; Irena L. Ivanovska, Joe Swift, Jerome Irianto, Kyle Spinler, Jae-Won Shin, Amnon Buxboim, and Dennis E. Discher

Intranuclear Measurement of Deformation in Single Cells; Jonathan T. Henderson and Corey P. Neu

CELLULAR AND MOLECULAR IMAGING METHODS: CHANNELS

Fluorescence Methods for Monitoring Mechanosensitive Channels; Alexander Macmillan, Charles G. Cranfield, and Boris Martinac

Channel Activation and Mechanotransduction; Henry J. Donahue, Randall L. Duncan, and Damian C. Genetos

CELLULAR AND MOLECULAR IMAGING METHODS: SURFACES AND SINGLE MOLECULE MEASUREMENTS

Characterization of Intermolecular and Intramolecular Interactions with the Atomic Force Microscope; Gil U. Lee, Krasimir Ivanov, Devrim Kilinc, Elena Martines, Agata Blasiak, Peng Li, and Michael J. Higgins

Characterization of Biomolecular Interactions with the Surface Forces Apparatus; Marina Ruths, Carlos Drummond, and Jacob N. Israelachvili

Magnetic Tweezers Force Spectroscopy; Eric A. Galburt

Analytical Electron Microscopy of Bone and Mineralized Tissue; Michal Klosowski, Alexandra E. Porter, Sandra J. Shefelbine, and David W. McComb

Optical Microscopy Methods for Measuring Structure and Dynamic Processes of Cells and Tissues; Elliot L. Elson

FABLE and Image Processing; Ali Nekouzadeh and Niloufar Ghoreishi

About the Editors

Corey Neu directs the Soft Tissue Bioengineering Laboratory at Purdue University and holds an appointment on the faculty in Purdue’s Weldon School of Biomedical Engineering. He earned a PhD in biomedical engineering from the University of California, Davis. Dr. Neu studies force transfer in cells and tissues in the context of disease and regeneration. His current research focuses on structural and mechanical changes to articular cartilage in the pathogenesis of osteoarthritis, and multiscale biomechanics and mechanobiology of collagen-rich tissues.

Guy Genin holds appointments on the faculty of the Department of Mechanical Engineering and Materials Science at Washington University in St. Louis, and the Department of Neurosurgery at the Washington University School of Medicine. Dr. Genin earned his PhD in applied and solid mechanics from Harvard University. He studies interfaces and adhesion in nature, physiology, and engineering. He is the recipient of numerous awards for engineering design, teaching, and research, including a Research Career Award from the National Institutes of Health and the Skalak Award from the American Society of Mechanical Engineers.

Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
SCI055000
SCIENCE / Physics
TEC059000
TECHNOLOGY & ENGINEERING / Biomedical