Handbook of Prebiotics: 1st Edition (Hardback) book cover

Handbook of Prebiotics

1st Edition

Edited by Glenn R. Gibson, Marcel Roberfroid

CRC Press

504 pages | 53 B/W Illus.

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pub: 2008-01-29
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In order to achieve optimal digestion, absorption, and nutritional health, we must have appropriate populations of positive microflora. Prebiotics are functional foods that improve health by fortifying indigenous probiotics within the gut. This fast-growing area of nutrition and microbiology is rapidly amassing data and answering many questions about the necessity and benefit of such functional foods.

Gathering contributions from leading experts in a range of disciplines, Handbook of Prebiotics presents a balanced view of the current knowledge in many different areas of the field. It discusses concept, definition and criteria for classification of a food component as prebiotics It then describes interactions with gut microbiota. Highlighting varying levels of evidence and agreement, the book presents current arguments for and against prebiotic intake. Contributions discuss the biomechanics of prebiotics and their effects on immune status, serum lipid concentrations, mineral bioavailability, and satiety modulation. They consider the health implications of prebiotic intake such as reduced incidence of gastroenteritis and chronic pathogenic gut disorders, including intestinal cancers and inflammatory bowel diseases.

Providing well-rounded coverage, the book explores the varying effects of prebiotics in different populations and age groups such as infants and the elderly, as well as livestock and pets. The final chapters describe food avenues and the safety implications for prebiotic use. Spanning several disciplines including food science, nutrition, microbiology, biotechnology, and the health sciences, this seminal work makes a point to include sound research science and well-balanced views on the potential of prebiotics for promoting good health.


"I would strongly recommend this book for food scientists, gastroenterologists interested in intestinal microecology, and anyone working in the prebiotic and probiotic industry."

– Martin H. Floch, Section of Digestive Diseases, Yale University School of Medicine, in Journal of Clinical Gastroenterology, Nov/ Dec 2008, Vol. 42, No. 10

Table of Contents


General Introduction: Prebiotics in Nutrition, M.B. Roberfroid

Gastrointestinal Microflora and Interactions with Gut Mucosa, A.L. Wells, D.M.A. Saulnier, and G.R. Gibson

Prebiotics: Concept, Definition, Criteria, Methodologies, and Products, M.B. Roberfroid

The Prebiotic Effect: Review of Experimental and Human Data, S. Kolida and G. Gibson

Effects of Prebiotics on Mineral Absorption: Mechanisms of

Action, I.J. Griffin and S.A. Abrams

Prebiotics and the Absorption of Minerals: A Review of Experimental and Human Data, K.M. Hawthorne and S.A. Abrams

Immune Functions and Mechanisms in the Gastrointestinal Tract, A. Dubert-Ferrandon, D.S. Newburg, and W.A. Walker

Prebiotics and the Immune System: Review of Experimental and Human Data, S. Seifert and B. Watzl

Triacylglycerols and Cholesterol Metabolism, M. Beylot, F. Forcheron, and D. Letexier

Prebiotics and Lipid Metabolism: Review of Experimental and Human Data, N.M. Delzenne and A.M. Neyrinck

Endocrinology of the Gastrointestinal Tract and Modulation of Satiety: Specific Focus on Glucagon-Like Peptide, R. Burcelin and P.D. Cani

Prebiotics and Modulation of Gastrointestinal Peptides, P.D. Cani, R. Burcelin, and C. Knauf

Designing Studies and Rodent Models for Studying Prebiotics for Colorectal Cancer Prevention, N.J. Emenaker and J.A. Milner

Colorectal Cancer Prevention: The Role of Prebiotics, A. Umar, N.J. Emenaker, and J.A. Milner

Prebiotics and Reduction of Risk of Carcinogenesis: Review of Experimental and Human Data, A. Klinder, M. Glei, and B.L. Pool-Zobel

Prebiotics and Cancer Therapy, H.S.Taper and M.B. Roberfroid

Pathophysiology of Inflammatory Bowel Diseases, F. Hoentjen and L.A. Dieleman

Prebiotics in Inflammatory Bowel Diseases, F. Guarner

Prebiotics and Infant Nutrition, Y. Vandenplas, T. Devreker, S. Salvatore, and B. Hauser

Prebiotics and Nutrition in the Elderly: The Concept of Healthy Ageing, I. Rowland and C. Gill

Prebiotics and Animal Nutrition, J. Van Loo

Food Applications of Prebiotics, A. Franck

Prebiotics and Food Safety, G. Pascal

Concluding Remarks, G.R. Gibson and M.B. Roberfroid


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