Handbook of Therapeutic Biomarkers in Cancer: 1st Edition (Hardback) book cover

Handbook of Therapeutic Biomarkers in Cancer

1st Edition

Edited by Sherry X. Yang, Janet E. Dancey

Jenny Stanford Publishing

518 pages | 20 Color Illus. | 18 B/W Illus.

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Hardback: 9789814364652
pub: 2013-06-21
eBook (VitalSource) : 9780429088452
pub: 2013-06-21
from $28.98

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In this volume, a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology.

Table of Contents

Overview: Therapeutic Biomarkers in Cancer, Sherry X. Yang and Janet E. Dancey

Statistical Considerations in the Development and Evaluation of Therapeutic Biomarkers in Cancer, Lisa M. McShane, Edward L. Korn and Boris Freidlin

Role of Biomarkers in Clinical Development of New Cancer Therapies, Helen X. Chen

HER2 as a Prognostic and Predictive Biomarker in Cancer, Suparna Wedam and Stan Lipkowitz

Hormone Receptors and Endocrine Therapy in Breast Cancer, Chia C. Portera and Sherry X. Yang

Predictive Biomarkers for Epidermal Growth Factor Receptor (EGFR) Agents in Non-Small Cell Lung Cancer, John Hilton, Penelope A. Bradbury, and Janet E. Dancey

Markers of Sensitivity and Resistance to EGFR Inhibitors in Colorectal Cancer, Jose G. Monzon and Janet E. Dancey

Targeting BCR-ABL for Molecular Therapy of Chronic Myelogenous Leukemia, Shamudheen Rafiyath, Guoqing Wei, and Delong Liu

Gastrointestinal Stromal Tumors (GISTs): From Molecular Pathogenesis to Therapy, Joaquina Baranda, Rashna Madan and Andrew K. Godwin

PML/RARa Fusion Gene and Response to Retinoic Acid and Arsenic Trioxide Treatment, Alicja Gruszka and Myriam Alcalay

Dihydropyrimidine Dehydrogenase Deficiency and 5-Fluouracil Toxicity, Eva Gross and André B. P. van Kuilenburg

UGT1A1 Polymorphisms and Mutations Lead to Irinotecan-Induced Toxicity, Kellie Reece and William D. Figg

The 21-Gene Recurrence Score and Benefit of Chemotherapy in Estrogen Receptor-Positive Breast Cancer, Petra Rietchel and Joseph A. Sparano

MammaPrint for Individualized Recurrence Risk Assessment and Treatment Recommendations for Early-Stage Breast Cancer Patients, Sonal J. Desai and Tianhong Li

BRCA mutation and PARP Inhibitors, Marcie K. Weil, Shivaani Kummar, James H. Doroshow, and Alice P. Chen

EML4-ALK Fusion Gene and Therapy with ALK-targeted Agents in Non-Small Cell Lung Cancer, Vimal Patel, MD and Biren Saraiya

BRAF-Targeted Therapy in Metastatic Melanoma, Noori Kim and April C. Deng

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Oncology
MEDICAL / Pathology
SCIENCE / Life Sciences / Cytology