1st Edition

Hemostasis and Animal Venoms

Edited By Hubert Pirkle, Francis S. Markham Copyright 1988
    658 Pages
    by CRC Press

    Assembling a broad range of current research findings on animal venoms that affect human hemostatic mechanisms, this reference offers a wealth of information on clinical research, including such medical applications as anticoagulant therapy and clinical laboratory testing, and fundamental research involving blood coagulation and platelet biology. Hemostasis and Animal Venoms details procoagulant venom factors ... thrombin-like enzymes ... fibrinogen and fibrinolytic activities ... venom inhibitors of proteolysis . . . hemostasis . . . platelet activating and aggregating factors ... hemorrhagic factors ... plus more. In addition, it furnishes a consistent framework for understanding innovative developments by coupling reviews with new research results. Illustrated with over 270 tables, diagrams, and photographs-including 8 color micrographs-and referenced with over 1,300 bibliographic citations of pertinent literature, Hemostasis and Animal Venoms is an important source for hematol­ogists, toxicologists, pharmacologists, biochemists and clinical chemists, internists, pathologists, and herpetologists.

    Contributors, Preface, 1. COAGULANT FACTORS, 11. FIBRINOLYSIS, III. INHIBITORS, IV. PLATELET ACTIVATION AND AGGREGATION, V. HEMORRHAGIC FACTORS, VI. OTHER LABORATORY STUDIES, VII. CLINICAL APPLICATIONS, Taxonomic Index, Subject Index

    Biography

    Hubert Pirkle is Professor of Pathology at the College of Medicine, University of California, Irvine. Formerly he taught at the University of Louisville (1955-70) and was a visiting investigator in the Department of Blood Coagulation Research at the Karolinska Institute in Stockholm, Sweden (1964-65). The author or coauthor of 75 articles, book chapters, and abstracts, most of them concerning the biochemistry of blood coagulation, he is a member of the American Association of Pathologists, American Chemical Society, American Heart Association Council on Thrombosis, International Academy of Pathologists, and International Society of Thrombosis and Haemostasis. Francis S. Markland Jr. is Professor of Biochemistry at the University of Southern California School of Medicine in Los Angeles, where he is also affiliated with the Comprehensive Cancer Center. An editorial council member of Toxicon, the International Journal of Toxinology, he is currently a member of the Biochemical Endocrinology Study Section of the National Institutes of Health.