1st Edition

Intestinal Microbiota in Health and Disease
Modern Concepts

ISBN 9781482226768
Published February 11, 2014 by CRC Press
344 Pages 10 Color & 3 B/W Illustrations

USD $200.00

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Book Description

Now considered an organ with defensive and metabolic capabilities, the intestinal microbiota plays a major role in the local host immune system development and education. It contributes to the generation of a homeostatic balance characterized by the capacity to react against pathogens while remaining hyperresponsive/tolerant against commensals. This homeostatic response depends on bacteria and bacterial product sensing by innate immune cells and their molecular asset at the intestinal mucosa. This book captures the enormous progress that has been accomplished in this field in recent years.

Table of Contents

Commensal Intestinal Microbiota and Mucosal Immune System Development and Function
Bacterial Imprinting of the Neonatal Immune System: Lessons From Maternal Cells. Interactions of the Intestinal Microbiota with the Epithelial Cells
Host Genotype, Environmental Factors and Microbiota Composition
Pathogen-Host Cell Interactions at the Intestinal Level: Lessons from Cultured Human Fully-Differentiated Colon Cancer Caco-2 and T84 Epithelial Cell Lines
Manipulation of the Host-Cell Pathways by Bacterial Entero-Pathogens
Use of Probiotic Cultures in Humans for the Management of Gastrointestinal Infections. Composition of the Dominant Microbiota During Flare-Ups and Remission of IBD
Opportunistic Pathogens in IBD, and the Relation with Specific Gene Susceptibilities
Opportunistic Pathogens in IBD, the Case of AIEC. Correction of Microbiota Disturbances or Antagonism against Specific Pathogens in IBD
Probiotics in IBD That Can Modulate the Pathological Immune/Inflammatory Activation
Their Potential Benefits in the Different Phases of the Disease
Fecal Microbiota in Patients Receiving Enteral Nutrition
How to Preserve a Healthy Intestinal Microbiota in the Intensive Care Patient
Dietary Factors, Microbiota in Relation with Overweight and Diabetes

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"Overall this is a nice resource."
—Koen Venema, in Beneficial Microbes

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