1st Edition

Mapping of Nervous System Diseases via MicroRNAs

Edited By Christian Barbato, Francesca Ruberti Copyright 2016
274 Pages
by CRC Press

274 Pages 17 B/W Illustrations
by CRC Press

274 Pages
by CRC Press

In recent years, understanding of microRNA (miRNA) biogenesis, the molecular mechanisms by which miRNAs regulate gene expression, and the functional roles of miRNAs has expanded. Mapping of Nervous System Diseases via MicroRNAs provides an up-to-date review on the function of miRNA in neurological diseases as well as advancements in technology for therapeutic modulation of miRNA activity.... Read more

MicroRNAs IN THE NERVOUS SYSTEM AND NEUROLOGICAL DISEASES (BASIC): MicroRNAs IN THE NERVOUS SYSTEM. MicroRNA Biology and Function in Nervous System. MicroRNAs IN THE NERVOUS SYSTEM AND NEUROLOGICAL DISEASES (BASIC): MicroRNAs IN NEUROPSYCHIATRIC DISEASES. MicroRNAs in Mood and Anxiety Disorders. MicroRNA Dysregulation in Schizophrenia and Functional Consequences. The Impact of MicroRNAs in Synaptic Plasticity, Major Affective Disorders, and Suicidal Behavior. MicroRNAs IN THE NERVOUS SYSTEM AND NEUROLOGICAL DISEASES (BASIC): MicroRNAs IN NEUROLOGICAL DISEASES. MicroRNAs in Prion Diseases. MicroRNAs in Epileptogenesis and Epilepsy. MicroRNAs and Pain. MicroRNA BIOMARKERS IN NEUROLOGICAL DISEASES (APPLICATIONS). Circulating Cell-Free MicroRNAs as Biomarkers for Neurodegenerative Diseases. Circulating Cell-Free MicroRNAs as Biomarkers for Neural Development and Its Importance in Fetal Programming for Postnatal Disease.

Biography

Christian Barbato, MD, is a researcher at the Institute of Cell Biology and Neurobiology, CNR, in Italy. He earned his PhD in neuroscience from the University of Rome Tor Vergata, Italy. His past work has focused on the characterization of cellular and molecular neurobiology of RNA-induced silencing complex and noncoding RNA in synaptic plasticity, learning, and memory. His recent research focuses on the function of microRNAs and their gene targets implicated in physiological and pathological processes of neurons.



Francesca Ruberti, PhD, is a researcher at the Institute of Cell Biology and Neurobiology, CNR, in Italy. He earned his PhD in biophysics from the International School of Advanced Studies, Trieste, Italy. His past research has focused on the role of nerve growth factor on specific neuronal populations of the central nervous system and on synaptic plasticity in the hippocampus, and on the molecular mechanisms involved in the cellular localization of specific neuronal proteins or messenger RNAs. His recent research focuses on the study of microRNAs and their gene targets implicated in physiological and pathological processes of neurons.