1st Edition

Microbial Enzymes and Metabolites for Health and Well-Being

    202 Pages 11 Color & 3 B/W Illustrations
    by CRC Press

    202 Pages 11 Color & 3 B/W Illustrations
    by CRC Press

    This up-to-date reference book discusses the synthesis, production, and application of various microbial enzymes and metabolites for health. Microorganisms like bacteria (lactic acid bacteria, Bacillus species), yeasts, and filamentous fungi have been globally exploited for their biotechnological applications. This book discusses ways to use them commercially. Chapters include the production of fibrinolytic enzymes, microbial lipases, bacteriocin production by lactic acid bacteria, and bioactives produced. It also covers microbial synthesis of alkaloids, terpenoids, and steroids. This book is useful for researchers, academicians, and industry experts in microbiology and biotechnology.

    Section I: Microbial Enzymes in Healthcare

    1. Microbial Enzymes and Metabolites in Health Care: An Overview

    Srichandan Padhi, Puja Sarkar, Md Minhajul Abedin, Ranjna Sirohi, Sudhir P Singh, and Amit Kumar Rai

    2. Microbial Production of Fibrinolytic Enzymes

    Kyoungseon Min and Ki-Yeon Kim

    3. Microbial Enzymes for Synthesis of Chiral Drug Intermediates

    K B Arun, Raveendran Sindhu, Bipin G Nair, Binod Parameswaran, Ashok Pandey, Mukesh Kumar Awasthi, Mohammed Kuddus, and Aravind Madhavan

    4. Microbial Enzymes in Biomedical Applications

    Ramzan Ahmed, Manjit Kumar Ray, Debasis Nayak, and Yugal Kishore Mohanta

    5. Microbial Lipases: Production and Application

    T P Sari, Vivek Kumar Gaur, Ayon Tarafdar, Ranjna Sirohi, Raveendran Sindhu, and Amit Kumar Rai

    6. Health Benefits of Bioactive Compounds Produced Using Microbial Enzymes

    Swati Sharma, Loreni Chiring Phukon, Rounak Chourasia, Ranjna Sirohi, Binod Parameswaran, Ashok Pandey, Dinabandhu Sahoo, and Amit Kumar Rai

    Section II: Microbial Metabolites in Healthcare

    7. Bacteriocin Production by Lactic Acid Bacteria

    Luciana Porto de Souza Vandenberghe, Bruna Leal Maske, Gilberto Vinícius de Melo Pereira, Leonardo Wedderhoff Herrmann, Luiz Alberto Junior Letti, and Carlos Ricardo Soccol

    8. Production and Application of Antimicrobial Compounds from Endophytes

    Poonam Kumari, Aishwarya Jaiswal, and Akanksha Singh

    9. Microbial Synthesis and Application of Terpenoids and Steroids

    Adriane Bianchi Pedroni Medeiros, Cristine Rodrigues, Denisse Molina-Aulestia, Guilherme Anacleto dos Reis, and Thalita de Oliveira Good

    10. Microbial Synthesis of Polypeptides and Applications in Healthcare

    T P Sari, Amresh Hindurao Dhamane, Prarabdh C Badgujar, Deepak Kumar, Ayon Tarafdar, Amit Kumar Rai, and Ranjna Sirohi

    11. Microbial Synthesis of Alkaloids and Applications in Healthcare

    K B Arun, Bipin G Nair, Raveendran Sindhu, Laya Liz Kuriakose, Binod Parameswaran, Ashok Pandey, Mukesh Kumar Awasthi, and Aravind Madhavan


    Ranjna Sirohi is a Research professor at the Korea University, Seoul, South Korea. She completed her PhD degree in Process and Food Engineering from G.B. Pant University of Agriculture and Technology, Pantnagar, India. She has worked as researcher at École Polytechnique Fédérale de Lausanne, Switzerland. Her major research interests are bioprocess technology, food & food waste valorisation, waste to wealth, biofuels. She has 94 publications including 60 research and review papers, 13 book chapters, seven popular articles and 14 conference proceedings, to her credit.

    Amit Kumar Rai is Scientist C at the Institute of Bioresources and Sustainable Development, Sikkim. He completed his doctorate from CSIR-CFTRI, Mysore. His major area of interest is food biotechnology for the production of nutraceuticals and functional foods rich in bioactive peptides and isoflavones using microorganisms. He has 3 patents, 76 publications, 3 books and 23 book chapters, to his credit.

    Luciana Porto de Souza Vandenberghe is a Full Professor at the Department of Bioprocess Engineering and Biotechnology, Federal University of Paraná, Curitiba, Brazil. She is a member of the Bioprocess Engineering and Biotechnology Graduation Program at UFPR. She obtained her PhD degree in Génie de Procédés Industriels - Biotechnologie from Université de Technologie de Compiègne (2000), France. Her areas of interest include Bioprocess Engineering & Biotechnology and Industrial Microbiology, with focus on valorization of solid and liquid agro-industrial subproducts through submerged and solid-state fermentation for biomolecules production including industrial enzymes, organic acids, biopolymers and plant growth hormones. She has published 123 papers, 51 book chapters and 23 deposed patents.

    Binod Parameswaran is a Principal Scientist in the Microbial Processes and Technology Division of CSIR-National Institute for Interdisciplinary Science and Technology, Trivandrum, India. He obtained Ph D in Biotechnology from University of Kerala, India. He worked as a Post-doctoral fellow at the Korea Institute of Energy Research, Daejeon, South Korea and later joined as Scientist at CSIR-National Institute for Interdisciplinary Science and Technology, India. His research interest includes biomass to fuels and chemicals, biopolymers and enzyme technology. He has more than 140 publications and an h-index of 45. His name is listed in the world’s top 2% scientist for the whole career as per the study by Stanford University and Elsevier in the year 2020.