Microelectrofluidic Systems: Modeling and Simulation, 1st Edition (Hardback) book cover

Microelectrofluidic Systems

Modeling and Simulation, 1st Edition

By Tianhao Zhang, Krishnendu Chakrabarty, Richard B. Fair

CRC Press

288 pages | 114 B/W Illus.

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pub: 2002-05-17
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Description

Composite systems that integrate microelectromechanical and microelectrofluidic (MEF) components with electronics are emerging as the next generation of system-on-a-chip (SOC) designs. However, there remains a pressing need for a structured methodology for MEFS design automation, including modeling techniques and simulation and optimization tools.

Integrating top-down and bottom-up design philosophies, Microelectrofluidic Systems presents the first comprehensive design strategy for MEFS. This strategy supports hierarchical modeling and simulation from the component level to the system level. It leads to multi-objective optimization tools valuable in all phases of the design process, from conceptualization to final manufacturing. The authors begin by defining the basic variables and elements needed to describe MEFS behavior, then model that behavior across three layers of abstraction: the low-level component, high-level reconfigurable architecture, and bio/chemical application layers. They have developed a hierarchical integrated design environment with SystemC and present its architecture and associated functional packages.

Microelectrofluidic Systems is visionary in its leverage of electronic design principles for microsystem design and heralds a new era of automated SOC design. The strategy it presents holds the potential for significant reductions in design time and life-cycle maintenance costs, and its techniques and tools for robust design and application flexibility can lead to the high-volume production needed for the inevitably growing product market.

Reviews

"[In this textbook] microelectrofluidic systems are thoroughly explained and defined in an understandable manner (which at times is challenging in an engineering text). … highly informative in its descriptive premise of top-down modeling and simulation…This text opens up a number of directions for research into top-down design for microelectrofluidic systems. … The information contained in the book will help achieve reduced costs and design stability for microelectrofluidic systems in an automated design market."

- IEEE Engineering in Medicine and Biology

Table of Contents

INTRODUCTION

Modeling and Simulation Issues

Modeling and Simulation Needs

Overview

HIERARCHICAL MODELING

MEFS Dynamic Modeling and Simulation at Circuit Level

MEFS System-Level Modeling and Simulation

Conclusion

SYSTEMC-BASED HIERARCHICAL DESIGN ENVIRONMENT

Suitability of Modeling Languages for Hierarchical Design

Building Design Environment with SystemC

Conclusion

SYSTEM-LEVEL SIMULATION AND PERFORMANCE EVALUATION

MEFS Computing and Architecture

Hierarchical Modeling and Simulation Methodology

Micro-Chemical Handling System

System Performance Analysis and Design Optimization

Conclusion

CIRCUIT-LEVEL OPTIMIZATION

Simulation Design Methodology

Optimization Verification

On-Target Design Optimization

Robust Design Optimization

Application Flexibility Optimization

Conclusion

PERFORMANCE EVALUATION

Introduction

Continuous-Flow PCR System

Droplet-Based PCR System

Comparison Between Continuous-Flow PCR and Droplet PCR

Scheduling of Microfluidic Operations for Reconfigurable Two-Dimensional Electrowetting Arrays

CONCLUSION

APPENDICES

VHDL Queuing Model

Hierarchical Environment with SystemC

Keywords: Nanoscience, Nanotechnology

About the Series

Nano- and Microscience, Engineering, Technology and Medicine

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Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
TEC008070
TECHNOLOGY & ENGINEERING / Electronics / Microelectronics
TEC027000
TECHNOLOGY & ENGINEERING / Nanotechnology & MEMS