The Classic Edition of this foundational text includes a new preface from Holly A. Tuokko, examining how the field of Mild Cognitive Impairment (MCI) has developed since first publication. Bringing together research from multiple studies and perspectives from various countries, the volume identifies MCI as an important clinical transition between normal aging and the early stages of Alzheimer's disease (AD).
The up-to-date preface highlights the expansion in research, examining the benefits of various pharmacological, cognitive and behavioral approaches to intervention. Influenced by recent findings in neuroplasticity across the lifespan, the book recognizes the importance of intervention at the earliest stages of the decline trajectory. It revisits the contested diagnostic approaches for MCI as well as the varying prevalence of MCI internationally, yet points to the need for further longitudinal studies to fully understand the condition.
Mild Cognitive Impairment continues to provide a comprehensive resource for clinicians, researchers and students involved in the study, diagnosis, treatment and rehabilitation of people with MCI.
Table of Contents
About the editors
List of contributors
From the series editor
Introduction to the Classic Edition
- An overview of mild cognitive impairment
HOLLY A. TUOKKO AND IAN MCDOWELL
General Population Research on MCI
2 The PAQUID study
COLETTE FABRIGOULE, PASCALE BARBERGER-GATEAU, AND JEAN-FRANÇOIS DARTIGUES
3 Cognitive impairment in elderly persons without dementia: Findings from the Kungsholmen Project
KATIE PALMER, LARS BACKMAN, BRENT J. SMALL, AND LAURA FRATIGLIONI
4 Population levels of mild cognitive impairment in England and Wales
JANE FLEMING, FIONA E. MATTHEWS, MARK CHATFIELD, AND CAROL BRAYNE
5 The Melbourne Aging Study
ALEXANDER COLLIE, PAUL MARUFF, DAVID G. DARBY, COLIN MASTERS, AND JON CURRIE
6 Mild cognitive impairment in the Religious Orders Study
ROBERT S. WILSON, NEELUM T. AGGARWAL, AND DAVID A. BENNETT
7 A perspective from the Mayo Clinic
GLENN SMITH, MARY MACHULDA, AND KEJAL KANTARCI
8 Prediction of probable Alzheimer's disease: The Sunnybrook Memory Study
MARY C. TIERNEY
9 Studies in the Leipzig Memory Clinic: Contribution to the concept of mild cognitive impairment
HENRIKE WOLF AND HERMANN-JOSEF GERTZ
10 Emerging pharmacological therapies for mild cognitive impairment
11 Cognition-based therapies and mild cognitive impairment
ROBERT T. WOODS AND LINDA CLARE
12 Combined therapies in mild cognitive impairment
KEVIN PETERS AND GORDON WINOCUR
Summary and Future Directions
13 The future of mild cognitive impairment
HOLLY A. TUOKKO AND DAVID F. HULTSCH
Holly A. Tuokko was a Professor in the Department of Psychology and Institute on Aging and Lifelong Health at the University of Victoria. She was awarded Senior Investigator status through the Canadian Institutes of Health Research, Institute of Aging (2002–2007), for her program of research on mental health and aging.
David F. Hultsch was a Professor of Psychology at the University of Victoria from 1984 onward, with a major research focus on cognition and aging. He was a founder of the journal Aging, Neuropsychology, and Cognition, serving as co-editor for 10 years.
"This valuable volume brings the kind of broad perspective to mild cognitive impairment that has long been needed. Rather than basing conclusions on a single sample or framework, the editors have pulled together articles from leading research groups around the world. This is the kind of comprehensive approach that is needed for developing systematic and valid definitions of MCI and identifying better tools that make it possible to differentiate between benign memory changes in later life and the early signs of pathological processes." - Steven H. Zarit, Department of Human Development and Family Studies, The Pennsylvania State University, USA
"This volume provides the most comprehensive overview of mild cognitive impairment currently available. The conceptual and methodological challenges for studying MCI are tackled with rigor, and the complexities of defining the syndrome are not underestimated. This book is certain to become a classic text for those studying or researching cognitive agin, MCI and dementia, and for clinicians seeking an authoritative reference on the clinical manifestations of MCI." - Kaarin J. Anstey, Centre for Mental Health Research, Australian National University, Australia
"The editors of this book have done a great job. The description of the issues is laid out in a well-written introduction, making the descriptions of the research papers very accessible, even to the less well-informed reader. The conclusion likewise pulled together the various strands, including defining what still needs to be done to further refine the concept of MCI." - Graham A. Jackson, Laverndale Hospital, Scotland. In Dementia, August, 2008